Evidence map›Paper›PMID 42282685›Full record

ArticlebioRxiv : the preprint server for biology2026

Network-Level Characterization of Spontaneous Calcium Activity in an In-Vitro Alzheimer's Disease Model.

Anna M Emenheiser, Emma Gentry, Huijing Xue, Phillip Alvarez, Kate M O'Neill, Kan Cao, Wolfgang Losert

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anna M EmenheiserInstitute for Physical Science and Technology, University of Maryland, College Park, Maryland 20742, United States.ORCID 0009-0003-8513-7195
Emma GentryDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland 20742, United States.ORCID 0009-0001-4533-232X
Huijing XueDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland 20742, United States.ORCID 0000-0002-4160-704X
Phillip AlvarezRobert E. Fischell Institute for Biomedical Devices, University of Maryland, College Park, MD 20742, USA.ORCID 0000-0003-2849-552X
Kate M O'NeillInstitute for Physical Science and Technology, University of Maryland, College Park, Maryland 20742, United States.ORCID 0000-0003-4397-5767
Kan CaoDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland 20742, United States.ORCID 0000-0002-5806-2939
Wolfgang LosertInstitute for Physical Science and Technology, University of Maryland, College Park, Maryland 20742, United States.ORCID 0000-0002-1792-7860

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The neurodegenerative disorder Alzheimer's disease (AD) is widely known for biomarkers such as amyloid beta plaques and tauopathy, as well as functional differences in memory and cognitive ability. Despite this devastating functional impact, a large body of work only focuses on molecular biomarkers of AD. In this study, we investigate collective neural dynamics

Indexed as

Alzheimer’s DiseaseCalcium ImagingIn VitroLiving Neural Networks

Identifiers

PMID42282685
PMCPMC13252383

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.