Evidence map›Paper›PMID 42282677›Full record

ArticlebioRxiv : the preprint server for biology2026

CD163 protects against pulmonary injury and inflammation induced by acute O

Samuel J Cochran, Brett Saunders, Evangeline Schott, Katelyn Dunigan-Russell, Grace M Hutton, Aaron Vose, Anastasiya Birukova, Cameron Rankin, Timothy J McMahon, Hongmei Zhu and 5 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Samuel J CochranDivision of Pulmonary, Critical Care, and Sleep Medicine, OSU Wexner Medical Center, Columbus, OH.ORCID 0000-0001-7314-4265
Brett SaundersDivision of Pulmonary, Critical Care, and Sleep Medicine, OSU Wexner Medical Center, Columbus, OH.ORCID 0009-0005-4325-4515
Evangeline SchottDivision of Pulmonary, Critical Care, and Sleep Medicine, OSU Wexner Medical Center, Columbus, OH.ORCID 0009-0004-2013-4249
Katelyn Dunigan-RussellDivision of Pulmonary, Critical Care, and Sleep Medicine, OSU Wexner Medical Center, Columbus, OH.ORCID 0000-0002-3383-8446
Grace M HuttonDivision of Pulmonary, Critical Care, and Sleep Medicine, OSU Wexner Medical Center, Columbus, OH.ORCID 0009-0004-1100-1786
Aaron VoseDepartment of Medicine, Duke University, Durham, NC.ORCID 0000-0003-2745-7070
Anastasiya BirukovaDepartment of Medicine, Duke University, Durham, NC.ORCID 0000-0001-9168-138X
Cameron RankinDepartment of Medicine, Duke University, Durham, NC.ORCID 0009-0003-8832-4666
Timothy J McMahonDepartment of Medicine, Duke University, Durham, NC.ORCID 0000-0002-3404-3223
Hongmei ZhuDepartment of Medicine, Duke University, Durham, NC.
Valery V KhramtsovDepartment of Biochemistry and Molecular Medicine, School of Medicine, West Virginia University, Morgantown, WV.ORCID 0000-0001-6187-5546
Murugesan VelayuthamDepartment of Biochemistry and Molecular Medicine, School of Medicine, West Virginia University, Morgantown, WV.ORCID 0009-0001-9751-538X
Salik HussainDepartment of Physiology, Pharmacology, and Toxicology, School of Medicine, West Virginia University, Morgantown, WV.ORCID 0000-0003-0339-6226
Robert M TigheDepartment of Medicine, Duke University, Durham, NC.ORCID 0000-0002-3465-9861
Kymberly M GowdyDivision of Pulmonary, Critical Care, and Sleep Medicine, OSU Wexner Medical Center, Columbus, OH.ORCID 0000-0002-7227-0697

Funding

Novel role for CD163 in ozone induced alterations of pulmonary immunityR01ES028829 · NIEHS · OHIO STATE UNIVERSITY · PI GOWDY, KYMBERLY MAE · 2018 to 2022
$2.7M
Integrative Research Training Program in Pediatric Cardiopulmonary DiseaseT32HL166149 · NHLBI · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI Carl Backes, Vidu Garg · 2023 to 2026
$1.4M
The role of NCOA4-mediated ferritinophagy in ozone-induced pulmonary ferroptosis.F32HL182295 · NHLBI · OHIO STATE UNIVERSITY · PI COCHRAN, SAMUEL J. · 2025 to 2025
$78k
NHLBI NIH HHS F32 HL182295NHLBI NIH HHS T32 HL166149NIEHS NIH HHS R01 ES028829
6 · The paper itself

Abstract

Ozone (O

Indexed as

CD163cell free hemoglobinlung inflammationozone

Identifiers

PMID42282677
PMCPMC13252149

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.