Evidence map›Paper›PMID 42282625›Full record

ArticlebioRxiv : the preprint server for biology2026

Shared biosynthetic architectures generate diverse β-amino polyketide residues in cyanobacterial peptides.

Aaditi Chopade, Anmol Chaure, Mary-Candler Schantz, Runjie Xia, David E Berthold, Forrest W Lefler, H Dail Laughinghouse, Matthew J Bertin

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Aaditi ChopadeDepartment of Chemistry, Case Western Reserve University, Cleveland, OH 44106, United States.
Anmol ChaureFaculty of Environmental Sciences, Czech University of Life Sciences, Prague, Czech Republic.
Mary-Candler SchantzDepartment of Chemistry, Case Western Reserve University, Cleveland, OH 44106, United States.
Runjie XiaDepartment of Chemistry, Case Western Reserve University, Cleveland, OH 44106, United States.
David E BertholdFort Lauderdale Research and Education Center, University of Florida - Institute of Food and Agricultural Sciences, Davie, FL 33314, United States.
Forrest W LeflerFort Lauderdale Research and Education Center, University of Florida - Institute of Food and Agricultural Sciences, Davie, FL 33314, United States.
H Dail LaughinghouseFort Lauderdale Research and Education Center, University of Florida - Institute of Food and Agricultural Sciences, Davie, FL 33314, United States.
Matthew J BertinDepartment of Chemistry, Case Western Reserve University, Cleveland, OH 44106, United States.

Funding

Shifting paradigms to emerging toxins in freshwater cyanobacterial bloomsR21ES033758 · NIEHS · UNIVERSITY OF RHODE ISLAND · PI BERTIN, MATTHEW JOHN · 2022 to 2023
$415k
NIEHS NIH HHS R21 ES033758
6 · The paper itself

Abstract

Cyanobacteria generate structurally complex peptides with diverse biological functions and vast chemical diversity, yet the enzymatic logic that produces their many documented unusual β-amino acid-containing polyketide units remains incompletely understood. Here we show that the recently described genus

Indexed as

BiochemistryBiological Sciencescomparative genomicshybrid PKS-NRPS biosynthesisSpecialized metabolites

Identifiers

PMID42282625
PMCPMC13252402

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.