Evidence map›Paper›PMID 42282602›Full record

ArticlebioRxiv : the preprint server for biology2026

Deep Proteoform Sequencing with Top-Down Direct Mass Technology.

Kenneth R Durbin, Taojunfeng Su, Ryan T Fellers, John P McGee, Nickolas P Fisher, Michael A R Hollas, Jared O Kafader, Neil L Kelleher

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kenneth R DurbinProteinaceous, Inc., Evanston, IL, 60201, United States.ORCID 0000-0001-7163-4877
Taojunfeng SuDepartments of Chemistry and Molecular Biosciences, Department of Chemical and Biological Engineering, the Chemistry of Life Processes Institute, the Proteomics Center of Excellence at Northwestern University, Evanston, Illinois 60208, United States.
Ryan T FellersProteinaceous, Inc., Evanston, IL, 60201, United States.
John P McGeeProteinaceous, Inc., Evanston, IL, 60201, United States.
Nickolas P FisherDepartments of Chemistry and Molecular Biosciences, Department of Chemical and Biological Engineering, the Chemistry of Life Processes Institute, the Proteomics Center of Excellence at Northwestern University, Evanston, Illinois 60208, United States.
Michael A R HollasProteinaceous, Inc., Evanston, IL, 60201, United States.
Jared O KafaderDepartments of Chemistry and Molecular Biosciences, Department of Chemical and Biological Engineering, the Chemistry of Life Processes Institute, the Proteomics Center of Excellence at Northwestern University, Evanston, Illinois 60208, United States.
Neil L KelleherDepartments of Chemistry and Molecular Biosciences, Department of Chemical and Biological Engineering, the Chemistry of Life Processes Institute, the Proteomics Center of Excellence at Northwestern University, Evanston, Illinois 60208, United States.ORCID 0000-0002-8815-3372

Funding

National Center for Translational and Developmental ProteomicsRM1GM156535 · NIGMS · NORTHWESTERN UNIVERSITY · PI NEIL L KELLEHER · 2025 to 2026
$3.4M
Data-Driven Software to Automate Top-Down Mass Spectrometry of Large MoleculesR44GM136046 · NIGMS · PROTEINACEOUS, INC. · PI DURBIN, KENNETH · 2023 to 2024
$1.9M
NIGMS NIH HHS R44 GM136046NIGMS NIH HHS RM1 GM156535
6 · The paper itself

Abstract

Individual Ion Mass Spectrometry (I

Identifiers

PMID42282602
PMCPMC13252097

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.