ArticlebioRxiv : the preprint server for biology2026
Distinct Auditory Thalamocortical Pathologies Underlie Emerging Neurophysiological Dysfunction in a Cln3 Mouse Model of Batten Disease.
Yanya Ding, Jingyu Feng, Viollandi Prifti, Grace A Rico, Alexander G Solorzano, Hayley E Chang, Samantha A Spallina, Edward G Freedman, John J Foxe, Kuan Hong Wang
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
10 authors.
Yanya DingDepartment of Neuroscience, University of Rochester Medical Center, Rochester, NY, 14642, USA.ORCID 0000-0002-6343-926X Jingyu FengDepartment of Neuroscience, University of Rochester Medical Center, Rochester, NY, 14642, USA.
Viollandi PriftiDepartment of Neuroscience, University of Rochester Medical Center, Rochester, NY, 14642, USA.
Grace A RicoDepartment of Neuroscience, University of Rochester Medical Center, Rochester, NY, 14642, USA.
Alexander G SolorzanoDepartment of Neuroscience, University of Rochester Medical Center, Rochester, NY, 14642, USA.
Hayley E ChangDepartment of Neuroscience, University of Rochester Medical Center, Rochester, NY, 14642, USA.
Samantha A SpallinaDepartment of Neuroscience, University of Rochester Medical Center, Rochester, NY, 14642, USA.
Edward G FreedmanDepartment of Neuroscience, University of Rochester Medical Center, Rochester, NY, 14642, USA.ORCID 0000-0001-8570-6325 John J FoxeDepartment of Neuroscience, University of Rochester Medical Center, Rochester, NY, 14642, USA.ORCID 0000-0002-4300-3098 Kuan Hong WangDepartment of Neuroscience, University of Rochester Medical Center, Rochester, NY, 14642, USA.ORCID 0000-0002-2249-5417 Funding
University of Rochester Intellectual and Developmental Disabilities Research CenterP50HD103536 · NICHD · UNIVERSITY OF ROCHESTER · PI JOHN J FOXE, Anna K Majewska · 2020 to 2026
$9.8MRochester Resource-Based Center for Bone, Muscle and Orthopaedic Research (ROCSTARR) (Overall Application)P30AR069655 · NIAMS · UNIVERSITY OF ROCHESTER · PI Edward M. Schwarz · 2016 to 2026
$7.8MNIAMS NIH HHS P30 AR069655NICHD NIH HHS P50 HD103536
6 · The paper itselfAbstract
CLN3 disease, the most common form of the Neuronal Ceroid Lipofuscinoses (NCLs), causes progressive cognitive decline and language impairment in humans. A pathological hallmark is the accumulation of storage material within neuronal lysosomes resulting from mutations in the
Indexed as
Age- and sex-dependent differencesAuditory duration mismatch negativity (MMN)Auditory evoked potential (AEP)Auditory thalamocortical circuitsCLN3 diseaseLysosomal storage disorderSubunit C of Mitochondrial ATP Synthase (SCMAS)
Identifiers
PMID42282513
PMCPMC13252151
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390