Evidence map›Paper›PMID 42282463›Full record

ArticleEuropean heart journal. Imaging methods and practice2026

Impact of coronary artery disease on systolic function in severe aortic stenosis-a multimodality imaging study.

Reetta Hälvä, Satu Vaara, Suvi Syväranta, Miia Holmström, Johanna Federico, Touko Kaasalainen, Juha Peltonen, Satu Suihko, Jyri Lommi, Heikki Niemi and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European heart journal. Imaging methods and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Reetta HälväRadiology, HUS Diagnostic Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Satu VaaraRadiology, HUS Diagnostic Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Suvi SyvärantaRadiology, HUS Diagnostic Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Miia HolmströmRadiology, HUS Diagnostic Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Johanna FedericoRadiology, HUS Diagnostic Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Touko KaasalainenRadiology, HUS Diagnostic Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Juha PeltonenRadiology, HUS Diagnostic Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Satu SuihkoHeart and Lung Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Jyri LommiHeart and Lung Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.ORCID https://orcid.org/0000-0002-8125-5499
Heikki NiemiHeart and Lung Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Valtteri UusitaloClinical Physiology and Nuclear Medicine, Helsinki University Hospital and University of Helsinki, Stenbäckinkatu 11, 00290 Helsinki, Finland.ORCID https://orcid.org/0000-0001-7345-7122

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: The aim of this study was to determine the impact of obstructive coronary artery disease (CAD) and diffuse atherosclerosis on left ventricular systolic function, measured as global longitudinal strain (GLS) by cardiac magnetic resonance (CMR) feature tracking, in patients with severe aortic stenosis (AS). Methods and results: In this single-centre prospective cohort study, patients with severe AS and transcatheter aortic valve implantation (TAVI) between October 2018 and February 2022 were referred for transthoracic echocardiography, CMR, and TAVI computed tomography. Invasive coronary angiography was performed before TAVI. Ninety-four patients (80 ± 7 years) were included. The prevalence of obstructive CAD was 20 (21%) patients. The mean GLS in patients with severe AS was -24.0 ± 6.1%, and the median coronary calcium score was 802 (interquartile range 302-2130). GLS was not reduced in patients with obstructive CAD compared to other patients (23.7 ± 5.9% vs. 24.1 ± 6.2%, Conclusion: GLS correlated with left ventricular mass and the presence of ischaemic scar, suggesting that intrinsic myocardial disease, rather than concomitant CAD alone, accounts for reduced GLS in this population.

Identifiers

PMID42282463
PMCPMC13253018

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.