ArticleBioinformation2026
Post-operative pain in molar teeth with symptomatic apical periodontitis using cryotreated neem extract and cryotreated 2.5% sodium hypochlorite: A randomised double-blinded clinical trial.
Article in Bioinformation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Post-operative pain following root canal treatment remains a significant clinical concern. Therefore, it is of interest to evaluate the effect of cryotherapy using sodium hypochlorite and neem extract on post-endodontic pain in 108 patients with symptomatic apical periodontitis undergoing single-visit treatment. Participants were divided into four groups: room temperature sodium hypochlorite, cryotreated sodium hypochlorite, room temperature neem extract and cryotreated neem extract and pain were assessed using the Visual Analogue Scale at 24 hours, 48 hours and 7 days. Cryotreated irrigants showed significantly lower pain scores at 24 and 48 hours compared to room temperature groups and neem extract demonstrated comparable efficacy to cryotreated sodium hypochlorite. Thus, the potential of cryotreated neem extract is shown as a biocompatible alternative irrigant for effective post-operative pain reduction.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.