ArticleBioinformation2026
The effects of zinc oxide eugenol, calcium hydroxide, bioactive glass, resin and bioceramic canal sealers on post-operative pain: A randomized clinical trial.
Article in Bioinformation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
Post-operative pain after root canal treatment is still a common clinical issue that can make patients less comfortable and less likely to accept endodontic therapy. Therefore, it is of interest to assess post-operative pain associated with five distinct root canal sealers- bioactive glass-based, bioceramic-based, calcium hydroxide-based, resin-based and zinc oxide eugenol-based-using single-rooted premolars exhibiting symptomatic apical periodontitis. Hence, a total of 135 patients were randomly assigned to five groups (n = 27) and pain was measured using the visual analog scale at different time points after surgery. Bioactive glass-based sealers had the lowest pain scores after surgery, while zinc oxide eugenol-based sealers had higher pain levels in the first few days after surgery. Over time, pain levels decreased slowly across all groups. Thus, bioactive sealers may help reduce pain immediately after root canal treatment.
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