Evidence map›Paper›PMID 42282345›Full record

ArticleBioinformation2026

Correlation between vitamin B12 levels and peripheral neuropathy in diabetic patients.

M D Irfan, Poonam Motwani, Ritika Agrawal, B Jayakrishnan, Parth Jani, Rosario Maristhanny García Ferrín, Souvik Sur, Ram Rattan Negi

Abstract read
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In one paragraph

Article in Bioinformation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

M D IrfanDepartment of Physiology, Santosh Deemed to be University, Ghaziabad, Delhi NCR, India.
Poonam MotwaniDepartment of Physiology, Government Medical College (GMC), Ratlam, Madhya Pradesh, India.
Ritika AgrawalDepartment of Anaesthesiology, Gajra Raja Medical College, Gwalior, Madhya Pradesh, India.
B JayakrishnanDepartment of Medicine, Educare Institute of Dental Sciences, Malappuram, Kerala, India.
Parth JaniDepartment of General Medicine, Government Medical College, Bhavnagar, Gujarat, India.
Rosario Maristhanny García FerrínDepartment of Medicine, Universidad Central del Ecuador, Ecuador.
Souvik SurDepartment of Chemistry, Teerthanker Mahaveer University, Moradabad, Uttar Pradesh, India.
Ram Rattan NegiDepartment of Biochemistry, AIIMS, Bhopal, Madhya Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic peripheral neuropathy is a common and debilitating complication of diabetes mellitus, significantly impacting the quality of life of affected individuals. Vitamin B12 is essential for nerve function and myelin synthesis and its deficiency can lead to neuropathy that resembles diabetic neuropathy. Long-term metformin use in diabetic patients increases the risk of vitamin B12 deficiency, making the relationship between the two critical to explore. The study evaluated the correlation between serum vitamin B12 levels and peripheral neuropathy in type 2 diabetes patients using clinical assessments and vitamin B12 measurement through a chemiluminescent immunoassay. Thus, we show the link between vitamin B12 deficiency and severity of peripheral neuropathy in type 2 diabetes patients on long-term metformin therapy.

Indexed as

diabetic peripheral neuropathy (DPN)metformin therapyneuropathy severitytype 2 diabetes mellitusVitamin B12 deficiency

Identifiers

PMID42282345
PMCPMC13252204

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.