ArticleBioinformation2026
Utility of procalcitonin versus CRP in early sepsis detection.
Article in Bioinformation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Early sepsis detection remains challenging despite biomarker advances, with CRP widely used but PCT emerging as superior for bacterial infections in emergency settings. Therefore, it is of interest to compare the diagnostic accuracy of PCT and CRP in 284 emergency patients with suspected sepsis, using Sepsis-3 criteria and ROC analysis within 2 hours of presentation. PCT achieved higher AUC (0.847, 95% CI 0.812-0.882) versus CRP (0.721, 95% CI 0.680-0.762; p<0.001), with optimal cutoffs PCT 0.5 ng/mL and CRP 50 mg/L showing similar sensitivity (78.2% versus 82.1%) but PCT superior specificity. Septic patients exhibited markedly elevated PCT (median 2.8±4.2 ng/mL versus 0.3±0.8 ng/mL, p<0.001) and a faster peak time (6.2±2.1h versus 12.4±4.8h, p<0.001) than CRP. These data shows PCT's superior early diagnostic performance for emergency sepsis and thus supporting its adoption as a primary biomarker over CRP.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.