Estimation of gut microbiome motif associated with active tuberculosis - A case control study.

Meenal Jain, Tanya Jain, Rajat Nayak, Talha Saad, Akash Wamanrao Karale, Mohammad Ilyas, Ravikant Arjariya

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Article in Bioinformation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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7 authors.

Meenal JainDepartment of Anaesthesiology, Bundelkhand Government Medical College Sagar, Madhya Pradesh, India.

Tanya JainDepartment of Anaesthesiology, R.D. Gardi Medical College, Ujjain, Madhya Pradesh, India.

Rajat NayakDepartment of Emergency Medicine, Bundelkhand Government Medical College Sagar, Madhya Pradesh, India.

Talha SaadDepartment of Respiratory Medicine, Bundelkhand Medical College Sagar, Madhya Pradesh, India.

Akash Wamanrao KaraleDepartment of surgery, Bundelkhand Medical College, Sagar, Madhya Pradesh, India.

Mohammad IlyasDepartment of Anaesthesia, Bundelkhand medical College Sagar, Madhya Pradesh, India.

Ravikant ArjariyaDepartment of Physiology, Bundelkhand Government Medical College, Sagar, Madhya Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis (TB) is the most tenacious health issue affecting individuals globally. Therefore, it is of interest to estimate gut microbiota motifs associated with the outbreak of active TB by incorporating the insights from human case-control data. 106 respondents were categorised into 2 groups: group A with TB and group B controls with 53 respondents in each category. The Shannon diversity index was substantially diminished in affected individuals. The active TB cases exhibited substantially decreased micro-biomes (P < 0.001). Thus, we show the need to develop microbiome-targeted strategies to reduce the incidence of active TB cases and improve their effective management.

Indexed as

dysbiosisgut-lung axisgut microbiotaTuberculosis (TB)

Identifiers

PMID42282286

DOI10.6026/973206300222083

PMCPMC13252283

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