ArticleTremor and other hyperkinetic movements (New York, N.Y.)2026
Longitudinal Intention Tremor Trajectories in Essential Tremor: A Comment.
Article in Tremor and other hyperkinetic movements (New York, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Continued Dialogue about the Clinical Heterogeneity and Degenerative Pathology That Characterizes the Essential Tremors.Tremor and other hyperkinetic movements (New York, N.Y.) · 2026Article
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2 authors.
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Abstract
We read with interest the recent prospective study by Louis et al. examining longitudinal changes in intention tremor severity in essential tremor. The study provides valuable data addressing an important and previously understudied question regarding whether intention tremor worsens over time. While the findings demonstrate a significant group-level increase in intention tremor severity, we urge caution in extending these clinical observations to conclusions about progressive cerebellar degeneration. In the absence of direct structural, imaging, or pathological evidence, longitudinal progression of a cerebellar-related clinical sign does not necessarily confirm underlying neurodegenerative changes. Furthermore, the substantial heterogeneity observed in tremor trajectories, with a considerable proportion of patients showing stable or improved intention tremor, suggests that progression is not uniform and may reflect phenotypic variability within essential tremor rather than a universal degenerative process. Future studies incorporating direct measures of cerebellar structure and function, along with longer follow-up and phenotypic stratification, will be important to clarify the relationship between intention tremor progression and underlying cerebellar pathology.
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