Evidence map›Paper›PMID 42282258›Full record

ArticleCase reports in hematology2026

Exploring the Origin of Cells in the Progression of Primary Myelofibrosis to Acute Myeloid Leukemia Case Report.

Philip Papayanis, Kara Conroy, Melissa Larson, Sunita Nathan, Celalettin Ustun

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in hematology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Philip PapayanisDepartment of Medicine, Division of Internal Medicine, Rush University Medical Center, Chicago, Illinois, USA, rush.edu.ORCID https://orcid.org/0009-0005-3649-9039
Kara ConroyDepartment of Medicine, Division of Hematology, Oncology and Cellular Therapy, Rush University Medical Center, Chicago, Illinois, USA, rush.edu.
Melissa LarsonDepartment of Medicine, Division of Hematology, Oncology and Cellular Therapy, Rush University Medical Center, Chicago, Illinois, USA, rush.edu.
Sunita NathanDepartment of Medicine, Division of Hematology, Oncology and Cellular Therapy, Rush University Medical Center, Chicago, Illinois, USA, rush.edu.
Celalettin UstunDepartment of Medicine, Division of Hematology, Oncology and Cellular Therapy, Rush University Medical Center, Chicago, Illinois, USA, rush.edu.ORCID https://orcid.org/0000-0001-6896-6213

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary myelofibrosis (PMF) is the clonal proliferation of common myeloid progenitor (CMP) cells and can transform into acute myeloid leukemia (AML). The exact transformation process and cell lines involved are not well-understood. A patient with PMF received an allogenic hematopoietic stem cell transplant (alloHCT) from his major ABO incompatible sibling and developed pure red cell aplasia that resolved when his blood type switched to that of his donor's. He relapsed with AML 10 months after alloHCT; interestingly, his blood type remained his donor's type. This supports that AML in this patient with PMF stemmed from more committed progenitors (myeloblasts) than CMP.

Indexed as

acute myelogenous leukemiacase reportcell lineageprimary myelofibrosis

Identifiers

PMID42282258
PMCPMC13249797

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.