Evidence map›Paper›PMID 42282254›Full record

ArticleJOSPT open2026

The association of lumbar paraspinal muscle size and quality with physical function, disability, and pain in adults with chronic low back pain.

Cristiane R Carlesso, Jaclyn M Sions, William J Anderst, Charity G Patterson, Allison M Voss, Luiza P Weissmann, Blake S Johnson, Michael J Schneider, Sara R Piva

Abstract read
In one paragraph

Article in JOSPT open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cristiane R CarlessoDepartment of Physical Therapy & Athletic Training, University of Utah. Salt Lake City, Utah, United States.
Jaclyn M SionsDepartment of Physical Therapy, University of Delaware. Newark, Delaware, United States.
William J AnderstDepartment of Orthopedic Surgery, University of Pittsburgh. Pittsburgh, Pennsylvania, United States.
Charity G PattersonDepartment of Physical Therapy, University of Pittsburgh. Pittsburgh, Pennsylvania, United States.
Allison M VossDepartment of Physical Therapy, University of Pittsburgh. Pittsburgh, Pennsylvania, United States.
Luiza P WeissmannDepartment of Physical Therapy, University of Pittsburgh. Pittsburgh, Pennsylvania, United States.
Blake S JohnsonDepartment of Physical Therapy, University of Pittsburgh. Pittsburgh, Pennsylvania, United States.
Michael J SchneiderDepartment of Community Health Services and Rehabilitation Science, University of Pittsburgh. Pittsburgh, Pennsylvania, United States.
Sara R PivaDepartment of Physical Therapy, University of Pittsburgh. Pittsburgh, Pennsylvania, United States.

Funding

Influence of inflammation-related genetic variants on PT treatment response in a population affected by CLBPU19AR076725 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SOWA, GWENDOLYN A, VO, NAM V · 2019 to 2023
$21.7M
University of Utah Program to Provide Pain Research Knowledge (UP3RK)T90DA062773 · NIDA · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Julie M Fritz, Adam Joseph Gordon · 2024 to 2026
$1.1M
University of Utah Program to Provide Pain Research Knowledge (UP3RK)R90DA062893 · NIDA · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Julie M Fritz · 2024 to 2026
$1.0M
NIAMS NIH HHS U19 AR076725NIDA NIH HHS R90 DA062893NIDA NIH HHS T90 DA062773
6 · The paper itself

Abstract

Objective: Chronic low back pain (LBP) is linked to reduced lumbar paraspinal muscle size and quality. Given their role in spinal stabilization, this study examined associations between lumbar paraspinal muscle morphology and physical function, disability, and pain in chronic LBP. Design: Cross-sectional study. Methods: Cross-sectional area (CSA) and attenuation of the erector spinae and multifidi (upper: L1-L3; lower: L4-S1), psoas and quadratus lumborum (L3) were measured from computed tomography images. Performance-based physical function was assessed using the Five Times sit-to-stand, 2-minute walk, 4-meter walk, active sit-up, and single-leg stance tests. Disability and symptoms were evaluated using the Oswestry Disability Index, Numerical Pain Rating Scale, and PainDETECT. Linear and logistic regression analyses were conducted, adjusting for age, sex, and body mass index (BMI). Results: We analyzed data from 193 adults (age 55.0 ±16.0 years; BMI 27.2 ±4.0; 55% female). Regarding CSA, lower erector spinae was associated with walking speed (β:.0001, p:.021), upper erector spinae with balance (β:.002, p:.039), lower multifidi with neuropathic symptoms (β:-.010, p:.030), and quadratus lumborum with abdominal endurance (β:-.006, p:.012). For attenuation, upper erector spinae was associated with abdominal endurance (β:.046, p:.047) and quadratus lumborum with balance (β:.046, p:.030). Conclusions: Lumbar paraspinal muscle morphology was associated with physical function and neuropathic symptoms in chronic LBP.

Indexed as

Computed TomographyDisabilityLow Back PainOutcome AssessmentPainParaspinal Muscles

Identifiers

PMID42282254
PMCPMC13251710

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.