Evidence map›Paper›PMID 42282221›Full record

ArticleJournal of medicine and life2026

Segmental instrumentation in spinal infections: evaluating the role of metal implants in treatment outcomes.

Bogdan Șendrea, Radu Josanu, Bogdan Gabriel Voicu, Sebastian Mihai Văleanu, Andrei Tudorache, Romică Cergan

Abstract read
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Article in Journal of medicine and life, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bogdan ȘendreaFoisor Clinical Hospital of Orthopedics, Traumatology and Osteoarticular TB, Bucharest, Romania.
Radu JosanuFoisor Clinical Hospital of Orthopedics, Traumatology and Osteoarticular TB, Bucharest, Romania.
Bogdan Gabriel VoicuFoisor Clinical Hospital of Orthopedics, Traumatology and Osteoarticular TB, Bucharest, Romania.
Sebastian Mihai VăleanuFoisor Clinical Hospital of Orthopedics, Traumatology and Osteoarticular TB, Bucharest, Romania.
Andrei TudoracheFoisor Clinical Hospital of Orthopedics, Traumatology and Osteoarticular TB, Bucharest, Romania.
Romică CerganFoisor Clinical Hospital of Orthopedics, Traumatology and Osteoarticular TB, Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spinal infections comprise a heterogeneous group of disorders involving the spinal column and adjacent neural elements, including spondylitis, discitis, spondylodiscitis, meningitis, myelitis, spinal epidural abscess, and infectious polyradiculopathy. The use of spinal instrumentation in infected fields remains a debated topic, although recent evidence suggests it may be safe when combined with adequate debridement and antibiotic therapy. Our objective was to evaluate the impact of segmental instrumentation on clinical, laboratory, and microbiological outcomes in patients undergoing surgery for spinal infections. We conducted a retrospective study of 98 adult patients who underwent surgical treatment for spinal infections between 2016 and 2024. Patients were divided into instrumented and non-instrumented groups based on intraoperative decision-making. Clinical outcomes, inflammatory markers, reoperation rates, and hospital stay were analyzed. The results showed that instrumentation was performed in 86 patients, while 12 patients underwent surgery without fixation. Instrumented patients showed comparable infection resolution and clinical recovery despite more severe preoperative presentations. Mean hospital stay was 18.79 days in the instrumented group and 17.91 days in the non-instrumented group. Inflammatory markers improved consistently in the instrumented group. Microbiological confirmation was achieved in approximately half of the cases. In conclusion, segmental instrumentation appears safe in the surgical management of spinal infections when combined with thorough debridement and targeted antibiotic therapy. Clinical outcomes are primarily influenced by infection control rather than the avoidance of implants.

Indexed as

MetalsProstheses and ImplantsSpinal DiseasesAdultAgedAnti-Bacterial AgentsDebridementFemaleHumansLength of StayMaleMiddle AgedRetrospective StudiesTreatment OutcomeAnti-Bacterial AgentsMetalsantibiotic therapyCRP, C-reactive proteinCT, computed tomographyENT, ear, nose, and throatESR, erythrocyte sedimentation rateHIV, human immunodeficiency virusintervertebral instabilityIV, intravenousmetal implantMRI, magnetic resonance imagingNTM, non-tuberculous mycobacteriaspinal infectionSSI, surgical site infectionsTB, tuberculosisWBC, white blood cell

Identifiers

PMID42282221
PMCPMC13252677

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.