In one paragraphArticle in medRxiv : the preprint server for health sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
15 authors.
Megan M McLaughlinDivision of Cardiology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0002-9259-2984 Emily S MillerDepartment of Obstetrics and Gynecology, Warren Alpert Medical School, Brown University, Providence, RI, USA.
William GrobmanDepartment of Obstetrics and Gynecology, Warren Alpert Medical School, Brown University, Providence, RI, USA.
George SaadeDepartment of Obstetrics and Gynecology, Eastern Virginia Medical School, Norfolk, VA, USA.ORCID 0000-0001-7925-5302 Matthew K HoffmanDepartment of Obstetrics and Gynecology, Columbia University, New York, NY, USA.
Lauren TheilenDepartment of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA.ORCID 0000-0002-5662-6040 Lynn M YeeFeinberg School of Medicine, Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Northwestern University, Chicago, IL, USA.ORCID 0000-0002-6274-0544 C Noel Bairey MerzBarbra Streisand Women's Heart Center, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.ORCID 0000-0002-9933-5155 Caroline E RouseDepartment of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Jessica M PageDivision of Maternal-Fetal Medicine, Intermountain Health, Salt Lake City, UT, USA.
Kelly ZafmanDepartment of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, University of Pennsylvania Health System, Philadelphia, PA, USA.
Alexandra BerraObstetrics and Gynecology, MetroHealth Medical Center/Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Janet M CatovDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0002-9551-851X Funding
UCLA Clinical and Translational Science InstituteUL1TR000124 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$57.0MClinical and Translational Science Collaborative of ClevelandUL1TR000439 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI KONSTAN, MICHAEL W. · 2012 to 2016
$50.0MStress and Racial Disparities in Preeclampsia - Clues from DNA Methylomic ProfilingU01HL145358 · NHLBI · RESEARCH TRIANGLE INSTITUTE · PI Rebecca Boehm McNeil · 2020 to 2026
$24.6MIndiana Clinical and Translational Sciences InstituteUL1TR001108 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI DENNE, SCOTT C., SHEKHAR, ANANTHA · 2013 to 2017
$23.3MPreterm Birth in Nulliparous Women: An Understudied Population at Great RiskU10HD063036 · NICHD · RESEARCH TRIANGLE INSTITUTE · PI PARKER, CORETTE BREEDEN · 2010 to 2015
$19.5MPregnancy as a Window to Future Cardiovascular Health: Adverse Pregnancy Outcomes Supplement RequestU10HL119991 · NHLBI · RESEARCH TRIANGLE INSTITUTE · PI PARKER, CORETTE BREEDEN · 2013 to 2018
$12.6MInstitute for Clinical and Translational ScienceUL1TR000153 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI COOPER, DAN M · 2012 to 2015
$12.1MUniversity of California, San Francisco/Kaiser Permanente Northern California Division of Research Building Interdisciplinary Research Careers in Women’s Health (BIRCWH) K12 ProgramK12AR084219 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Monica Gandhi, CYNTHIA C HARPER · 2023 to 2026
$3.1MPrevention of Preterm Birth in high Risk Nulliparous PatientsU10HD063047 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WAPNER, RONALD · 2010 to 2014
$1.9MPreterm Birth in Nulliparous Women: An Understudied Population at Great RiskU10HD063053 · NICHD · UNIVERSITY OF UTAH · PI SILVER, ROBERT M. · 2010 to 2014
$1.7MPreterm Birth in Nulliparous Women: An Understudied Population at Great Risk U10HD063020 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GROBMAN, WILLIAM ADAM · 2010 to 2014
$1.6MPreterm Birth in Nulliparous Women: An Understudied Population at Great RiskU10HD063046 · NICHD · UNIVERSITY OF CALIFORNIA-IRVINE · PI WING, DEBORAH A · 2010 to 2014
$1.6MNCATS NIH HHS UL1 TR000124NCATS NIH HHS UL1 TR000153NCATS NIH HHS UL1 TR000439NCATS NIH HHS UL1 TR001108NHLBI NIH HHS K23 HL159316NHLBI NIH HHS U01 HL145358NHLBI NIH HHS U10 HL119989NHLBI NIH HHS U10 HL119990NHLBI NIH HHS U10 HL119991NHLBI NIH HHS U10 HL119992NHLBI NIH HHS U10 HL119993NHLBI NIH HHS U10 HL120006NHLBI NIH HHS U10 HL120018NHLBI NIH HHS U10 HL120019NHLBI NIH HHS U10 HL120034NIAMS NIH HHS K12 AR084219NICHD NIH HHS U10 HD063020NICHD NIH HHS U10 HD063036NICHD NIH HHS U10 HD063037NICHD NIH HHS U10 HD063041NICHD NIH HHS U10 HD063046NICHD NIH HHS U10 HD063047NICHD NIH HHS U10 HD063048NICHD NIH HHS U10 HD063053NICHD NIH HHS U10 HD063072
6 · The paper itselfAbstract
Background: Individuals diagnosed with depression during pregnancy are more likely to develop cardiovascular disease (CVD) later in life. However, it remains unclear whether subclinical depressive symptoms or symptom trajectories across time are associated with indicators of cardiovascular health (CVH). Therefore, the present study evaluated the relationship between longitudinal depressive symptom trajectories beginning in pregnancy and future CVH. Methods: This secondary analysis of the multisite prospective nuMoM2b-Heart Health Study and included participants with complete longitudinal data from early pregnancy to 2-7 years post-delivery. Participants self-reported depressive symptoms using the Edinburgh Postnatal Depression Scale (EPDS) at 6-13 weeks gestation (early pregnancy), 22-29 weeks gestation (mid- to late-pregnancy), and 2-7 years post-delivery. Latent class mixture modeling was conducted to identify longitudinal patterns of depressive symptoms across early pregnancy, mid-late pregnancy, and extended postpartum follow-up. Structural equation modeling was used to test whether EPDS trajectories were associated with latent CVH, adjusted for length of follow-up interval, pre-pregnancy BMI, gravidity, adverse pregnancy outcomes, smoking history, age, education, income, and use of psychiatric medications. Results: A total of 3,934 participants (mean ( Discussion: The longitudinal course of depressive symptoms from pregnancy to 2-7 years post-delivery varied across individuals. Compared to those with consistently low depressive symptoms, individuals with higher severity symptoms at any point all exhibited lower CVH, regardless of the specific trajectory of symptoms. These findings support a life-course perspective in which depressive symptom patterns may represent an early indicator of cardiometabolic vulnerability.
Indexed as
cardiovascular healthdepressionperinatal mental healthpregnancy
Identifiers
PMID42282160
PMCPMC13252446
What OpenQuestion holds
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