Evidence map›Paper›PMID 42282140›Full record

ArticleOrthopedic reviews2026

Algorithm-Based Surgical Decision-Making for Focal Knee Cartilage Defects: A Pragmatic Clinical Framework with Illustrative Cases.

Birzhan Suiindik, Yerik Raimagambetov, Kazybek Baktybergen, Dina Saginova, Meruert Makhmetova, Gulzhanat Korganbekova

Abstract read
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Article in Orthopedic reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Birzhan SuiindikDepartment of Orthopaedics National Scientific Center of Traumatology and Orthopaedics named after N.D. Batpenov.ORCID https://orcid.org/0009-0005-1835-8785
Yerik RaimagambetovDepartment of Orthopaedics National Scientific Center of Traumatology and Orthopaedics named after N.D. Batpenov.ORCID https://orcid.org/0009-0007-9856-7724
Kazybek BaktybergenDepartment of Trauma and Orthopedics Nazarbayev University School of Medicine.ORCID https://orcid.org/0009-0001-0610-9571
Dina SaginovaDepartment of Orthopaedics National Scientific Center of Traumatology and Orthopaedics named after N.D. Batpenov.ORCID https://orcid.org/0000-0001-9551-5354
Meruert MakhmetovaDepartment of Orthopaedics National Scientific Center of Traumatology and Orthopaedics named after N.D. Batpenov.ORCID https://orcid.org/0009-0004-3044-7724
Gulzhanat KorganbekovaDepartment of Orthopaedics National Scientific Center of Traumatology and Orthopaedics named after N.D. Batpenov.ORCID https://orcid.org/0000-0002-9600-9477

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To evaluate the early clinical and radiological outcomes of an algorithm-based surgical decision-making framework for focal knee cartilage defects using reproducible, cost-effective techniques in routine clinical practice. Materials and Methods: This retrospective case series included five consecutive patients with ICRS Grade 3-4 chondral or osteochondral lesions. Treatment followed a structured decision-making algorithm based on fragment viability, lesion size, and patient-specific factors. Surgical procedures included bone marrow stimulation (BMS, n=2), osteochondral autograft transplantation (OAT, n=1), and osteochondral fragment refixation for osteochondritis dissecans (OCD, n=2). Clinical outcomes were assessed using the Visual Analogue Scale (VAS) and the Knee Injury and Osteoarthritis Outcome Score (KOOS) at 1, 3, and 6 months. Structural repair was evaluated at 6 months using MRI-based MOCART 2.0 scoring. Results: All patients demonstrated progressive clinical improvement. Mean VAS scores decreased from 6.6 preoperatively to 1.2 at 6 months. KOOS scores improved across all subscales, with the greatest gains observed in activities of daily living. MRI evaluation demonstrated variable structural maturation (mean MOCART 2.0 score: 60, range 45-75), with superior outcomes observed in patients undergoing fragment refixation. Even in an older patient with extensive pathology, bone marrow stimulation resulted in satisfactory short-term outcomes. Conclusion: The proposed algorithm-based approach provides a practical and reproducible framework for selecting surgical treatment in focal knee cartilage defects. Despite the limited sample size, the consistent clinical improvement supports the feasibility and applicability of this decision-making model, particularly in real-world and resource-constrained settings.

Indexed as

bone marrow stimulationcartilage repairkneeMOCARTosteochondral autograftosteochondritis dissecans

Identifiers

PMID42282140
PMCPMC13252960

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.