Evidence map›Paper›PMID 42282059›Full record

ReviewEuropean heart journal open2026

Definitions and outcomes reported in studies investigating the management of new onset atrial fibrillation in acutely unwell patients admitted to the intensive care unit: a scoping review.

Brian W Johnston, Joby Mathew, Calum Voller, Ruaraidh A Hill, Bronagh Blackwood, Karen Williams, Angela Hall, Keith Wilson, Trudie H Lobban, Gregory Y H Lip and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in European heart journal open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Brian W JohnstonDepartment of Cardiovascular and Metabolic Medicine, Institute of Life Course and Medical Sciences, University of Liverpool, 6 West Derby Street, Liverpool L78TX, UK.ORCID https://orcid.org/0000-0003-1634-3297
Joby MathewLiverpool School of Medicine, University of Liverpool, Cedar House, Ashton Street, Liverpool L69 3GE, UK.
Calum VollerLiverpool School of Medicine, University of Liverpool, Cedar House, Ashton Street, Liverpool L69 3GE, UK.
Ruaraidh A HillLiverpool Reviews and Implementation Group (LRiG), University of Liverpool, Department of Health Data Science, Institute of Population Health, Waterhouse Building, Block B, Brownlow Building, Block B, Liverpool L69 3GF, UK.
Bronagh BlackwoodWellcome Wolfson Institute for Experimental Medicine, Queens University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK.
Karen WilliamsUniversity Hospitals of Liverpool Group, Royal Liverpool University Hospital, Department of Critical Care Medicine, Mount Vernon Street, Liverpool L78YE, UK.
Angela HallUniversity Hospitals of Liverpool Group, Royal Liverpool University Hospital, Department of Critical Care Medicine, Mount Vernon Street, Liverpool L78YE, UK.
Keith WilsonLiverpool Heart and Chest Hospital NHS Foundation Trust, Thomas Drive, Liverpool L14 3PE, UK.
Trudie H LobbanArrhythmia Alliance, Heart Rhythm Alliances and STARS, Celixir House, Stratford Business and Technology Park, Innovation Way, Stratford upon Avon, Warickshire CV37 7GZ, UK.
Gregory Y H LipDepartment of Cardiovascular and Metabolic Medicine, Institute of Life Course and Medical Sciences, University of Liverpool, 6 West Derby Street, Liverpool L78TX, UK.ORCID https://orcid.org/0000-0002-7566-1626
Ingeborg D WeltersDepartment of Cardiovascular and Metabolic Medicine, Institute of Life Course and Medical Sciences, University of Liverpool, 6 West Derby Street, Liverpool L78TX, UK.ORCID https://orcid.org/0000-0002-3408-8798

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

New-onset atrial fibrillation (NOAF) frequently occurs in critically ill patients admitted to intensive care units (ICUs), yet definitions and outcome reporting remain inconsistent across clinical studies. This heterogeneity impedes evidence synthesis and limits the development of standardized management strategies. A scoping review was conducted following the Arksey and O'Malley framework and reported using PRISMA-ScR guidelines. Electronic databases were searched from 1990 to 2024 for randomized controlled trials and observational studies reporting on NOAF in acutely unwell ICU patients. Data on arrhythmia definitions and reported outcomes were extracted and categorized using the ISPOR framework. This is the first study to systematically examine and compare diagnostic criteria for NOAF in ICU-based research. Out of 8477 records, 44 studies (4 RCTs, 12 prospective, and 28 retrospective observational studies) met inclusion criteria. Significant heterogeneity was found in how NOAF was defined, including arrhythmia duration thresholds, diagnostic criteria, and heart rate cut-offs. Outcomes were primarily clinician-reported (

Indexed as

Core outcome setCritical careISPORNew-onset atrial fibrillationOutcome measuresScoping review

Identifiers

PMID42282059
PMCPMC13252546

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.