ArticleIntegrative medicine research2026
Clinical evidence on integrated Chinese-Western medicine for depressive disorder.
Article in Integrative medicine research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- AI-empowered clinical evidence for integrated Chinese-Western medicine: Introduction to the ACE-iMed series and platform dissemination.Integrative medicine research · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Despite growing interest, evidence on integrated Chinese-Western medicine for depressive disorder (DD) remains fragmented, with no comprehensive summary across treatment modalities and evidence levels. Therefore, we summarized evidence to systematically delineate and visualize the scope, distribution, methodological quality, and results of clinical evidence on integrated Chinese-Western medicine for DD. Methods: Adhering to the AI-empowered Clinical Evidence for Integrated Chinese-Western Medicine (ACE-iMed) framework, a dedicated database for DD was established. Four major categories of traditional Chinese medicine intervention were included, namely Chinese herbal medicine, acupuncture, moxibustion, and Chinese movement exercise. Eight clinical questions (CQs) with predefined outcomes were formulated, each undergoing a systematic process of targeted searching, screening, and rigorous methodological quality assessment. The search strategy involved comprehensive querying of databases and regulatory websites up to September 6, 2025. Eligible evidence types were restricted to clinical practice guidelines/consensus statements (CPGs/CSs), systematic reviews (SRs) and randomized controlled trials (RCTs). Results: From an initial 41,137 records, 1402 studies were analyzed, with RCTs constituting the majority (n = 1232; 87.9%). While comprehensive evidence summaries for all eight CQs are presented on the ACE-iMed platform, this study focused on two representative CQs (CQ1 and CQ7). Overall, Chinese medicine treatment modalities, whether as monotherapy or in combination with conventional Western therapy, demonstrated enhanced efficacy and a favorable safety profile for DD. Conclusion: Using ACE-iMed, we summarized comprehensive evidence on integrated Chinese-Western medicine for DD, demonstrating favorable efficacy and safety and calling for high-quality studies to validate these findings and enable clinical translation in Hong Kong and beyond.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.