Evidence map›Paper›PMID 42281869›Full record

ArticleWorld journal of transplantation2026

Long-term renal function and complication profiles after ABO-incompatible

Beatriz Gil Braga, Ana Cunha, Manuela Almeida, Sofia Sousa, Ana Filipa Trigo, António Inácio, Bruno Dias, José Silvano, Catarina Ribeiro, Sofia Pedroso and 3 more

Abstract read
In one paragraph

Article in World journal of transplantation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Beatriz Gil BragaDepartment of Nephrology, Unidade Local de Saúde de Santo António, Porto 4099-001, Portugal. u14104@chporto.min-saude.pt.
Ana CunhaDepartment of Nephrology, Unidade Local de Saúde de Santo António, Porto 4099-001, Portugal.
Manuela AlmeidaDepartment of Nephrology, Unidade Local de Saúde de Santo António, Porto 4099-001, Portugal.
Sofia SousaDepartment of Nephrology, Hospital Divino Espírito Santo, Ponta Delgada 9500-370, Azores, Portugal.
Ana Filipa TrigoDepartment of Nephrology, ULS Médio Tejo, Torres Novas 2304-909, Santarém, Portugal.
António InácioDepartment of Nephrology, Unidade Local de Saúde da Arrábida, Setubal 2910-446, Portugal.
Bruno DiasDepartment of Nephrology, Unidade Local de Saúde de Santo António, Porto 4099-001, Portugal.
José SilvanoDepartment of Nephrology, Unidade Local de Saúde de Santo António, Porto 4099-001, Portugal.
Catarina RibeiroDepartment of Nephrology, Unidade Local de Saúde de Santo António, Porto 4099-001, Portugal.
Sofia PedrosoDepartment of Nephrology, Unidade Local de Saúde de Santo António, Porto 4099-001, Portugal.
Marco SampaioDepartment of Immunohemotherapy, Unidade Local de Saúde de Santo António, Porto 4099-001, Portugal.
Marika Bini-AntunesDepartment of Immunohemotherapy, Unidade Local de Saúde de Santo António, Porto 4099-001, Portugal.
La Salete MartinsDepartment of Nephrology, Unidade Local de Saúde de Santo António, Porto 4099-001, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundABO-incompatible (ABOi) kidney transplantation expands the living-donor pool but may increase immunologic and infectious risks. Advances in desensitization have improved outcomes, yet long-term comparative data remain limited. We hypothesized that ABOi living-donor kidney transplantation achieves renal function and complication rates comparable to ABO-compatible (ABOc) procedures under modern protocols.

aimTo assess whether long-term renal function and complication profiles remain comparable between ABOi and ABOc living-donor kidney transplant recipients.

methodsA retrospective single-center cohort study was conducted in a Portuguese transplant program, including all adult living-donor kidney transplants from January 2014 to December 2022 (follow-up to June 2023). A total of 208 recipients were included: 22 ABOi and 186 ABOc, excluding human leukocyte antigen-incompatible or high immunologic risk cases. Continuous variables were compared using Mann-Whitney

resultsMedian follow-up was 57 months. Five-year patient survival was 92.9% [95% confidence interval (CI): 79.4-100] in ABOi and 90.3% (95%CI: 85.5-95.2) in ABOc (

conclusionABOi transplantation achieved outcomes comparable to ABOc living-donor transplantation under contemporary desensitization protocols. These findings support the safety and efficacy of ABOi transplantation, while ongoing multicenter follow-up is needed to confirm long-term safety.

Indexed as

ABO-incompatible kidney transplantationDesensitization protocolEstimated glomerular filtration rateGraft survivalLiving donor transplantationPatient survivalProteinuria

Identifiers

PMID42281869
PMCPMC13250781

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.