Evidence map›Paper›PMID 42281867›Full record

ArticleWorld journal of transplantation2026

Donor size and early vascular complications in children receiving a whole liver transplant.

Irene Dieguez Hernandez Vaquero, Alba Bueno Jimenez, Areej M Salim, Hector Vilca-Melendez, Rebeca Sanabria Mateos, Joseph J Valamparampil, Evelyn Ong, Girish L Gupte, Khalid Sharif

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Article in World journal of transplantation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Irene Dieguez Hernandez VaqueroLiver Unit, Birmingham Children's Hospital, Birmingham B4 6NH, United Kingdom. dieguez.irene@nhs.net.
Alba Bueno JimenezLiver Unit, Birmingham Children's Hospital, Birmingham B4 6NH, United Kingdom.
Areej M SalimLiver Unit, Birmingham Children's Hospital, Birmingham B4 6NH, United Kingdom.
Hector Vilca-MelendezLiver Unit, Birmingham Children's Hospital, Birmingham B4 6NH, United Kingdom.
Rebeca Sanabria MateosLiver Unit, Birmingham Children's Hospital, Birmingham B4 6NH, United Kingdom.
Joseph J ValamparampilLiver Unit, Birmingham Children's Hospital, Birmingham B4 6NH, United Kingdom.
Evelyn OngLiver Unit, Birmingham Children's Hospital, Birmingham B4 6NH, United Kingdom.
Girish L GupteLiver Unit, Birmingham Children's Hospital, Birmingham B4 6NH, United Kingdom.
Khalid SharifLiver Unit, Birmingham Children's Hospital, Birmingham B4 6NH, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEarly vascular complications are one of the leading causes of morbidity and graft loss in paediatric whole liver transplant (WLT). It has been previously suggested that the donor size might influence these outcomes, but evidence remains insufficiently defined.

aimTo evaluate the influence of donor weight on the incidence of early vascular complications after WLT in paediatric recipients.

methodsSingle-centre, retrospective cohort study on patients under 18 years old, who received a first WLT between 2000 and 2024. Recipients were classified according to the donor's weight: Subgroups A (≤ 15 kg) and B (> 15 kg). Demographic, anthropometric, surgical and perioperative variables were analysed, focusing on early vascular complications - hepatic artery thrombosis (HAT), portal vein thrombosis (PVT) - and the need for re-transplantation within 30 days postoperatively.

resultsSixty-four patients met the inclusion criteria. Subgroup A (

conclusionIn paediatric WLT, grafts from small donors appear more susceptible to early vascular complications, reflecting the technical and anatomical vulnerability of small-calibre vessels rather than donor weight alone. Awareness of this relationship may assist in graft selection, intraoperative planning and postoperative surveillance.

Indexed as

Hepatic artery thrombosisPortal vein thrombosisRe-transplantationWhole liver transplant

Identifiers

PMID42281867
PMCPMC13250773

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