Evidence map›Paper›PMID 42281863›Full record

ReviewWorld journal of transplantation2026

Preconditioning with sufentanil confers protective effects in transplantation by attenuating hepatic ischemia-reperfusion injury.

Christina Mouratidou, Efstathios T Pavlidis, Georgios Katsanos, Athanasios Kofinas, Alexandra G Marneri, Kalliopi E Stavrati, Georgios Tsoulfas, Theodoros E Pavlidis

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World journal of transplantation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Christina MouratidouDepartment of Intensive Care Unit, Hippokration General Hospital, Thessaloniki 54642, Greece.
Efstathios T PavlidisThe Second Department of Propaedeutic Surgery, Hippokration General Hospital, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki 54642, Greece.
Georgios KatsanosDepartment of Transplantation Surgery, Center for Research and Innovation in Solid Organ Transplantation, Aristotle University of Thessaloniki, School of Medicine, Thessaloniki 54642, Greece.
Athanasios KofinasDepartment of Transplantation Surgery, Center for Research and Innovation in Solid Organ Transplantation, Aristotle University of Thessaloniki, School of Medicine, Thessaloniki 54642, Greece.
Alexandra G MarneriDepartment of Intensive Care Unit, Hippokration General Hospital, Thessaloniki 54642, Greece.
Kalliopi E StavratiDepartment of Surgical, Eugenideio Hospital, Athens 11528, Greece.
Georgios TsoulfasDepartment of Transplantation Surgery, Center for Research and Innovation in Solid Organ Transplantation, Aristotle University of Thessaloniki, School of Medicine, Thessaloniki 54642, Greece.
Theodoros E PavlidisThe Second Department of Propaedeutic Surgery, Hippokration General Hospital, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki 54642, Greece. pavlidth@auth.gr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatic ischemia-reperfusion injury (HIRI) is a significant contributor to liver dysfunction and failure following liver transplantation and hepatic surgical procedures. With the increasing global incidence of end-stage liver disease necessitating transplantation, strategies to mitigate HIRI have become important. Ferroptosis, a regulated form of cell death characterized by iron dependency and lipid peroxidation, has recently been recognized as a pivotal mechanism underlying hepatocellular injury during ischemia-reperfusion events. Emerging evidence suggests that in the context of HIRI, ferroptosis is facilitated by the convergence of iron overload, compromised antioxidant defenses, and excessive generation of lipid reactive oxygen species. Notably,

Indexed as

FerroptosisHepatic ischemia-reperfusion injuryHepatocellular injuryIron metabolismLipid peroxidationLiver transplantationOxidative stressSufentanil

Identifiers

PMID42281863
PMCPMC13250778

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.