Evidence map›Paper›PMID 42281855›Full record

ArticleWorld journal of transplantation2026

Microbiological spectrum and probability of transmission of infection from ocular tissues of enucleated eyes harvested from septicemic donors.

Aditi Dubey, Priyanka, Deepak Soni, Deepti Chaurasia, Brindha Periasamy, Nikhila C Jain, Deepayan Sarkar, Mamta Singh, Srishti Khullar, Kavita Kumar and 2 more

Abstract read
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Article in World journal of transplantation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Aditi DubeyDepartment of Ophthalmology, Gandhi Medical College Bhopal, Bhopal 462001, Madhya Pradesh, India.
PriyankaDepartment of Ophthalmology, All India Institute of Medical Sciences Bhopal, Bhopal 462020, Madhya Pradesh, India.
Deepak SoniDepartment of Ophthalmology, All India Institute of Medical Sciences Bhopal, Bhopal 462020, Madhya Pradesh, India.
Deepti ChaurasiaDepartment of Microbiology, Gandhi Medical College Bhopal, Bhopal 462001, Madhya Pradesh, India.
Brindha PeriasamyDepartment of Ophthalmology, All India Institute of Medical Sciences Bhopal, Bhopal 462020, Madhya Pradesh, India.
Nikhila C JainDepartment of Ophthalmology, All India Institute of Medical Sciences Bhopal, Bhopal 462020, Madhya Pradesh, India.
Deepayan SarkarDepartment of Ophthalmology, All India Institute of Medical Sciences Bhopal, Bhopal 462020, Madhya Pradesh, India.
Mamta SinghDepartment of Ophthalmology, All India Institute of Medical Sciences, Rajkot 360110, Gujarāt, India.
Srishti KhullarDepartment of Ophthalmology, Military Hospital, Agra 282001, Uttar Pradesh, India.
Kavita KumarDepartment of Ophthalmology, Gandhi Medical College Bhopal, Bhopal 462001, Madhya Pradesh, India.
Pragyil ChaturvediDepartment of Ophthalmology, All India Institute of Medical Sciences Bhopal, Bhopal 462020, Madhya Pradesh, India.
Bhavana SharmaDepartment of Ophthalmology, All India Institute of Medical Sciences Bhopal, Bhopal 462020, Madhya Pradesh, India. drbhavana_s@yahoo.co.in.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTissues from septicemic donor are considered contraindication for transplantation. However, a definite evidence is lacking to link these corneas as a potential source of post-transplantation infection.

aimTo assess corneal tissue microbiology in septicemic donors and correlate postmortem blood cultures with ocular isolates to determine transplant suitability.

methodsA bicentric cross-sectional study evaluated 264 eyes from 136 septicemic and non-septicemic donors at two eye banks of tertiary eye centers. Culture report of tissue samples (conjunctival swab, aqueous and vitreous tap, cornea, sclera, and post- mortem blood sample) was compared with the culture results of post-mortem blood samples. Additionally, correlation if any was evaluated between culture positivity of harvested tissue with death to retrieval time. Statistical results were analyzed using Pearson

resultsAmong 21 septicemic donors, microbial growth was observed in 28.6%, 7.1%, 9.5%, 4.8%, and 2.4% of non-utilized conjunctival, corneal, scleral, aqueous, and vitreous samples respectively as opposed to 16.7 [odds ratio (OR) = 10.6, 95% confidence interval (CI): 0.938-4.263,

conclusionThese findings suggest that sepsis does not significantly impact ocular tissue sterility. Thus, current transplantation guidelines may benefit from further review, particularly in light of the potential to increase the availability of transplantable tissue, consequent to reduced rejection and wastage.

Indexed as

Corneal blindnessCorneal transplantationDonor tissue contaminationEye bankingSepticemia

Identifiers

PMID42281855
PMCPMC13250791

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