Evidence map›Paper›PMID 42281831›Full record

ArticleChemical science2026

High-dimensional CRISPR-SERS interactomics tracks the topological evolution of plant viral pathogenesis and therapeutic response.

You Dou, Gang Wu, Jun Li, Yuting Wang, Nanke Chen, Tianbing Xu, Xiaobo Cai, Tuotuo Zhang, Xinwei Zhang, Xiangyang Li and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

You DouCollege of Chemistry, Central China Normal University Wuhan 430079 China junrong.li@ccnu.edu.cn.
Gang WuThe Department of Radiology, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology China.
Jun LiCollege of Chemistry, Huazhong Agricultural University Wuhan 430070 China.ORCID https://orcid.org/0009-0001-5075-2978
Yuting WangNational Key Laboratory of Agricultural Microbiology, College of Biomedicine and Health, Huazhong Agricultural University Wuhan 430070 China sunyaogbasp@ccnu.edu.cn.
Nanke ChenCollege of Chemistry, Central China Normal University Wuhan 430079 China junrong.li@ccnu.edu.cn.
Tianbing XuNational Key Laboratory of Agricultural Microbiology, College of Biomedicine and Health, Huazhong Agricultural University Wuhan 430070 China sunyaogbasp@ccnu.edu.cn.
Xiaobo CaiState Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University Guiyang 550025 China xyli1@gzu.edu.cn.
Tuotuo ZhangCollege of Chemistry, Central China Normal University Wuhan 430079 China junrong.li@ccnu.edu.cn.
Xinwei ZhangCollege of Chemistry, Central China Normal University Wuhan 430079 China junrong.li@ccnu.edu.cn.
Xiangyang LiState Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University Guiyang 550025 China xyli1@gzu.edu.cn.
Junrong LiCollege of Chemistry, Central China Normal University Wuhan 430079 China junrong.li@ccnu.edu.cn.ORCID https://orcid.org/0000-0002-1502-1811
Yao SunCollege of Chemistry, Central China Normal University Wuhan 430079 China junrong.li@ccnu.edu.cn.ORCID https://orcid.org/0000-0002-6519-7436

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Precision agriculture is currently limited by a reliance on viral load quantification, a static metric that obscures the dynamic molecular arms race between invading pathogens and host immunity. To overcome this limitation, we present a multidimensional surface-enhanced Raman spectroscopy (SERS) platform designed to map the real-time topology of the host-virus interactome. Overcoming the spectral constraints of conventional assays, we engineered a

Identifiers

PMID42281831
PMCPMC13251604

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.