Evidence map›Paper›PMID 42281721›Full record

ArticleCureus2026

Genetic Polymorphisms and Pesticide Exposure-Related Health Manifestations Among Grape Farmers in Maharashtra, India.

Aishwarya Garud, Satyajeet Pawar, Kailas Datkhile, Pratik P Durgawale, Satish V Kakade, Satish R Patil

Abstract read
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aishwarya GarudDepartment of Molecular Biology and Genetics, Krishna Institute of Medical Sciences, Krishna Vishwa Vidyapeeth (Deemed to Be University), Karad, IND.
Satyajeet PawarDepartment of Microbiology, Krishna Institute of Medical Sciences, Krishna Vishwa Vidyapeeth (Deemed to Be University), Karad, IND.
Kailas DatkhileDepartment of Genetics, Krishna Institute of Science and Technology, Krishna Vishwa Vidyapeeth (Deemed to Be University), Karad, IND.
Pratik P DurgawaleDepartment of Molecular Biology and Genetics, Krishna Institute of Medical Sciences, Krishna Vishwa Vidyapeeth (Deemed to Be University), Karad, IND.
Satish V KakadeDepartment of Community Medicine, Krishna Institute of Medical Sciences, Krishna Vishwa Vidyapeeth (Deemed to Be University), Karad, IND.
Satish R PatilDepartment of Microbiology, Krishna Institute of Medical Sciences, Krishna Vishwa Vidyapeeth (Deemed to Be University), Karad, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Occupational exposure to pesticides has been associated with a range of adverse health outcomes among agricultural workers. Genetic polymorphisms in detoxification and DNA repair pathway genes may influence individual susceptibility to these effects. Grape farmers in southwestern Maharashtra, India, represent a high-risk occupational group facing routine and intensive pesticide exposure throughout the cultivation season, yet molecular epidemiological data from this population remain limited. Methods A cross-sectional exploratory study was conducted among 204 pesticide-exposed grape farmers from Sangli and nearby districts of southwestern Maharashtra, India. Demographic characteristics, exposure patterns, and self-reported symptoms experienced following pesticide exposure were recorded using a structured questionnaire. Oxidative stress markers, including malondialdehyde (MDA) and ferric reducing antioxidant power (FRAP), were measured as secondary biological indicators. Genotyping of paraoxonase 1 (

Indexed as

dna repair genesgenetic polymorphismoccupation healthparaoxonase 1pesticide exposurepesticide toxicity

Identifiers

PMID42281721
PMCPMC13250891

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.