ArticleCureus2026
Maternal Characteristics Associated With Congenital Anomalies: An Exploratory Case Series in a Secondary Care Hospital.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Congenital anomalies are a public health concern and the leading cause of infant mortality, particularly in low- and middle-income countries. Established risk factors include pregestational diabetes, maternal obesity, folic acid deficiency, and limited access to prenatal care. The aim of this exploratory study was to describe maternal characteristics in relation to isolated and multiple non-syndromic congenital anomalies in a series of cases from a secondary-care hospital in Puebla, Mexico. Materials and methods An observational, cross-sectional, exploratory case series with ambispective data collection was conducted in the Genetics Department of General Hospital Zone No. 20 of the Mexican Social Security Institute in Puebla, Mexico. The study included 31 mothers of patients with non-syndromic congenital anomalies. Data collected included sociodemographic characteristics, anthropometric measurements, and environmental exposures. Congenital anomalies were categorized as isolated or multiple. Categorical variables were compared using Fisher's exact test and continuous variables using the Mann-Whitney U test. Results A total of 31 mothers of patients with congenital anomalies were analyzed. Twenty-one (67.7%) cases presented isolated anomalies, and 10 (32.3%) multiple anomalies, with craniofacial anomalies being the most frequent. The mean maternal age at the time of pregnancy was 27.71 ± 5.58 years. Higher frequencies were observed among mothers with higher educational attainment, employment, and exposure to teratogens; however, these differences did not reach statistical significance. Conclusion In this exploratory case series, no statistically significant differences were found between maternal characteristics and the presence of isolated or multiple congenital anomalies. Observed differences should be interpreted in the context of the study design and limited sample size, and these findings are hypothesis-generating and require confirmation in larger, controlled studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.