Evidence map›Paper›PMID 42281572›Full record

ArticleNational science review2026

A fast method for breeding by design via G × E interactions detected in large-scale climatic, phenomic and genomic data.

Jing-Tian Wang, Xue-Lian Han, Miao-Miao Zhao, Han-Qing Zhang, Ying Chen, Qiu-Yun Jiang, Yuan-Ming Zhang

Abstract read
In one paragraph

Article in National science review, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jing-Tian WangCollege of Plant Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.ORCID https://orcid.org/0009-0005-4682-3445
Xue-Lian HanCollege of Plant Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.ORCID https://orcid.org/0009-0002-4817-2605
Miao-Miao ZhaoCollege of Plant Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Han-Qing ZhangCollege of Plant Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Ying ChenCollege of Plant Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Qiu-Yun JiangCollege of Plant Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Yuan-Ming ZhangCollege of Plant Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.ORCID https://orcid.org/0000-0003-2317-2190

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although large-scale populations are used to detect genes for polygenic traits, few studies integrate genes and gene-by-environment interactions (GEIs) into breeding by design. Here, we present Fast3VmrMLM, which uses eight big-data techniques to analyze climatic, phenomic and genomic data together to detect GEIs, decipher plasticity and guide breeding. In multi-environment joint analysis (MEJA) of maize, rice and soybean datasets, a total of 396 known genes and 84 known GEIs validated Fast3VmrMLM. In a 12-environment maize dataset, six GEIs interacting with five meteorological factors and two MEJA-detected GEIs helped to explain flowering time plasticity. Thirteen known genes, eight known GEIs and seven plasticity genes advanced flowering by 1.10-6.61 days, whereas nine known genes, one known GEI and three plasticity genes increased yield by 0.51-3.56 Mg·ha

Indexed as

climate changecropsgene-by-meteorological factor interactiongenome-wide association studylarge-scale datamachine learning

Identifiers

PMID42281572
PMCPMC13249571

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.