Evidence map›Paper›PMID 42281443›Full record

ArticleClinical endoscopy2026

Percutaneous endoscopic gastrostomy with jejunal extension versus direct percutaneous endoscopic jejunostomy: patient-related outcomes and complications.

Giel J L van Neerven, Eline H T Gilissen, Roos Gielen, Arlinda Baars, Bianca M L Stelten, Hajo Flink, Lennard P L Gilissen

Abstract read
In one paragraph

Article in Clinical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Giel J L van NeervenDepartment of Gastroenterology and Hepatology, Catharina Hospital Eindhoven, Eindhoven, The Netherlands.
Eline H T GilissenDepartment of Gastroenterology and Hepatology, Catharina Hospital Eindhoven, Eindhoven, The Netherlands.
Roos GielenDepartment of Gastroenterology and Hepatology, Catharina Hospital Eindhoven, Eindhoven, The Netherlands.
Arlinda BaarsDepartment of Gastroenterology and Hepatology, Catharina Hospital Eindhoven, Eindhoven, The Netherlands.
Bianca M L SteltenDepartment of Neurology, Catharina Hospital Eindhoven, Eindhoven, The Netherlands.
Hajo FlinkDepartment of Gastroenterology and Hepatology, Catharina Hospital Eindhoven, Eindhoven, The Netherlands.
Lennard P L GilissenDepartment of Gastroenterology and Hepatology, Catharina Hospital Eindhoven, Eindhoven, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPercutaneous endoscopic gastrostomy with jejunal extension (PEG-J) and direct percutaneous endoscopic jejunostomy (D-PEJ) are used for jejunal feeding or administration of levodopa-carbidopa intestinal gel in patients with Parkinson's disease. PEG-J is currently preferred because it is technically less challenging to insert. However, comparative studies are scarce, and data on patient-reported outcomes (PROMs) are limited.

methodsIn this retrospective study conducted at a referral hospital, clinical experience, adverse events (AEs), and PROMs associated with both techniques were evaluated.

resultsNinety-three patients underwent PEG-J and/or D-PEJ placement between January 1, 2010, and July 1, 2022. Patients with PEG-J required significantly more re-endoscopies per tube-year than those with D-PEJ (0.63 [standard deviation, SD, 0.72] vs. 0.27 [SD 0.50]). A total of 76.8% of PEG-J patients underwent at least one re-endoscopy (range, 0-3.85 per year), primarily due to dislocated jejunal extensions (77.4%). Tube-related AEs (including dislocation, occlusion, perforation, and ulceration) occurred significantly more often after PEG-J insertion (76.7% vs. 25.9%). Forty-five patients (48%) completed the PROM questionnaire. No statistically significant differences were found in quality of life. However, D-PEJ patients reported significantly more tube-related pain (44.4% vs. 15.9%).

conclusionsD-PEJ represents a viable alternative to PEG-J in experienced centers and should be considered when frequent complications with jejunal extensions occur.

Indexed as

ComplicationGastrostomyJejunostomyQuality of life

Identifiers

PMID42281443
PMCPMC13439301

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.