Evidence map›Paper›PMID 42281412›Full record

ReviewEuropean journal of oral sciences2026

Remarkable decline and sustained low levels of caries in the Nordic populations-Explanations and implications for public oral health.

Bente Nyvad, Ole Fejerskov

Abstract readReview
In one paragraph

Review in European journal of oral sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Bente NyvadDepartment of Dentistry and Oral Health, Section of Oral Ecology, Aarhus University, Aarhus, Denmark.ORCID 0000-0002-9545-0447
Ole FejerskovDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.ORCID 0009-0009-8810-0383

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Community water fluoridation has been acclaimed as an effective mode of caries control at the population level. However, a recent review has concluded that in high-income populations with widespread access to topical fluorides, water fluoridation (0.7 ppm F) has a minor effect on the development of caries. It may therefore be relevant to take a historical look at the benefits of an oral health intervention that does not rely on the use of systemic fluorides, such as toothbrushing with fluoride toothpaste. We summarize the evidence from large population studies in the Nordic countries during the past 50-yr and show that it is possible to obtain and sustain low caries levels over decades by self-performed use of fluoride toothpaste. Topical fluoride at low concentrations treats/arrests active/progressing caries lesions by controlling mineral loss in dental hard tissues, thereby reducing the development of cavities. Toothbrushing with fluoride toothpaste shifts the entire caries distribution to the left, including the right-hand tail end of the distribution, ensuring that also the more disadvantaged groups may benefit. Daily brushing with fluoride toothpaste should be promoted and trained through school-based oral health programs for children. It is time for a reappraisal of fluoride toothpaste for public oral health.

Indexed as

Dental CariesOral HealthPublic HealthCariostatic AgentsFluoridationFluoridesFluorides, TopicalFluoride TreatmentHumansScandinavian and Nordic CountriesToothbrushingToothpastesCariostatic AgentsFluoridesFluorides, TopicalToothpastescaries distributioncommunity water fluoridationfluoride toothpastemechanism of fluoride actionschool‐based toothbrushing

Identifiers

PMID42281412
PMCPMC13377909

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.