ArticleAnatolian journal of cardiology2026
Outcomes of Percutaneous Interventions for Aortic Coarctation: Experience from a Tertiary Care Center.
Article in Anatolian journal of cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
backgroundCoarctation of the aorta (CoA) is a congenital obstructive anomaly that may remain undiagnosed until adulthood, often presenting with systemic hypertension. While percutaneous interventions, including balloon angioplasty and stent implantation, are increasingly utilized in adults, real-world data on procedural outcomes, complications, and long-term mortality remain limited. This study aimed to evaluate procedural outcomes, complication rates, and short- and long-term mortality associated with percutaneous interventions in adult patients with CoA.
methodsA single-center, retrospective observational study was conducted, including adult patients with CoA who underwent percutaneous intervention between July 2017 and July 2023. Procedural success was defined as a residual peak systolic gradient ≤20 mmHg without major complications. Patient demographics, comorbidities, procedural details, complications, and follow-up outcomes were analyzed.
resultsTwenty-nine patients (median age 40 [29-45] years; 31% female) were included. Endovascular stent placement was performed in 89.7% of patients, 74% of whom were covered stents (mean length 39 mm). Balloon angioplasty alone was used in 10.3% of cases. The procedure was associated with a marked reduction in the peak systolic gradient, decreasing from a median of 57.5 mmHg [50.0-68.8] before the procedure to 9.0 mmHg [1.2-11.8] after the procedure. Complications occurred in 6.9%, including 1 aortic rupture and 1 access site bleeding. Recoarctation developed in 14% of patients at a median of 17.5 months. No in-hospital deaths occurred; out-of-hospital mortality was 6.9%, including 1 death of unknown cause and 1 following posterior mediastinal hematoma after aortic rupture.
conclusionsPercutaneous interventions in adult CoA achieve favorable procedural success and low in-hospital mortality, while rare but serious complications underscore the necessity for meticulous management and lifelong follow-up.
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