Evidence map›Paper›PMID 42280928›Full record

ReviewSensors (Basel, Switzerland)2026

Dynamic DNA Nanomachines for Biosensing and Drug Delivery.

Borui Zhang, Mengyao Sun, Jie Chao

Abstract readReview
In one paragraph

Review in Sensors (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Borui ZhangState Key Laboratory for Flexible Electronics (LoFE), Nanjing University of Posts and Telecommunications, Nanjing 210023, China.ORCID 0009-0000-2339-0791
Mengyao SunState Key Laboratory for Flexible Electronics (LoFE), Nanjing University of Posts and Telecommunications, Nanjing 210023, China.
Jie ChaoState Key Laboratory for Flexible Electronics (LoFE), Nanjing University of Posts and Telecommunications, Nanjing 210023, China.

Funding

National Natural Science Foundation of China 2024YFA1209402National Natural Science Foundation of China 22274081
6 · The paper itself

Abstract

DNA nanotechnology exploits the high precision and programmability of base complementary pairing to construct diverse nanostructures. Especially, the integration of stimuli-responsive modules has driven the evolution of DNA nanostructures toward dynamic nanomachines, conferring significant advantages in biomedical applications. In this review, the stimulus-response strategies of DNA nanostructures are first outlined, including molecular-driven mechanisms and environmental stimulation methods. The recent advances in the application of nanomachines based on various response strategies in biosensing and drug delivery are then elaborated. Finally, current challenges and prospects for these nanomachines in clinical diagnosis and precision therapy are discussed. This review provides a systematic reference for the development of responsive DNA nanomachines and the exploration of their biomedical applications.

Indexed as

Biosensing TechniquesDNA NanostructuresDrug Delivery SystemsDNAHumansNanotechnologyDNAbiosensingDNA nanostructuresdrug deliverydynamic nanomachinesstimulus-response strategies

Identifiers

PMID42280928
PMCPMC13258996

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.