ArticleNutrients2026
Water Distribution in the Body as a Source of Information on Markers of Skeletal Muscle Ageing.
Article in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesBody water, including its distribution between the intracellular (ICW) and extracellular (ECW) compartments, plays an important role in skeletal muscle physiology. The aim of this study was to assess whether body water distribution indices, namely ECW/ICW and ECW/TBW, differ according to age and sex, and whether they are associated with skeletal muscle index (SMI) after adjustment for BMI, age, and sex.
methodsThe study included 188 healthy individuals: 71 older women (71.6 ± 6.4 years), 37 older men (72.7 ± 4.7 years), 40 female students (22.5 ± 0.9 years), and 40 male students (22.8 ± 1.8 years). Body composition was assessed using a Tanita MC-780 bioimpedance analyser. The ECW/ICW and ECW/TBW ratios were calculated. Nonparametric analyses, Kendall's rank correlations, and linear regression models adjusted for BMI, age, and sex were used.
resultsOlder adults had significantly higher ECW/ICW and ECW/TBW values than younger participants, and women had higher values than men within the same age groups. Both indices correlated positively with age and BMI, and negatively with SMI. In multivariate models, ECW/TBW remained negatively associated with SMI after adjustment. BMI and male sex correlated positively with SMI, whereas age was not a significant predictor.
conclusionsBody water distribution indices (ECW/ICW, ECW/TBW) reflect age- and sex-related differences in water distribution and correlate with SMI independently of BMI, age, and sex. They may serve as complementary markers of skeletal muscle ageing.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.