Evidence map›Paper›PMID 42280284›Full record

ArticleMolecules (Basel, Switzerland)2026

OV16 Improves Radiation-Induced Intestinal Injury by Targeting Transglutaminase 2.

Zhiyan Zhang, He Wang, Yaowen Cui, Yang Lu, Yingying Xu, Min Li, Sifan Liu, Ying Tian, Ziming Xia, Guangjie Zhang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zhiyan ZhangCollege of Life Sciences, Hebei University, Baoding 071002, China.
He WangAcademy of Military Medical Sciences, Beijing 100850, China.
Yaowen CuiAcademy of Military Medical Sciences, Beijing 100850, China.
Yang LuCollege of Life Sciences, Hebei University, Baoding 071002, China.
Yingying XuAcademy of Military Medical Sciences, Beijing 100850, China.
Min LiAcademy of Military Medical Sciences, Beijing 100850, China.
Sifan LiuAcademy of Military Medical Sciences, Beijing 100850, China.
Ying TianAcademy of Military Medical Sciences, Beijing 100850, China.
Ziming XiaAcademy of Military Medical Sciences, Beijing 100850, China.
Guangjie ZhangAcademy of Military Medical Sciences, Beijing 100850, China.
Shuchen LiuCollege of Life Sciences, Hebei University, Baoding 071002, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Irradiation (IR) can cause intestinal epithelial cell death, damage to crypt stem cells, and mucosal barrier dysfunction, which are the features of radiation-induced intestinal injury (RIII). Our study first discovered a natural small-molecule alkaloid

Indexed as

GTP-Binding ProteinsIntestinal MucosaIntestinesRadiation InjuriesRadiation-Protective AgentsTransglutaminasesCell LineCell MovementCell ProliferationHumansMolecular Docking SimulationMolecular Dynamics SimulationProtein Glutamine gamma Glutamyltransferase 2GTP-Binding ProteinsProtein Glutamine gamma Glutamyltransferase 2Radiation-Protective AgentsTGM2 protein, humanTransglutaminasesOrychophragmus violaceusOV16radiation-induced intestinal injury (RIII)Transglutaminase 2 (TGM2)

Identifiers

PMID42280284
PMCPMC13257430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.