ArticleMolecules (Basel, Switzerland)2026
Synthesis of Novel Acetylene-Containing Phosphonates, Their Antiviral Activity, and Their Cytotoxicity to Different Cancer Cell Lines.
Anastasia V Egorova, Anastasia M Lobova, Dmitrii M Egorov, Elizaveta A Tishchenko, Alexandrina S Volobueva, Iana L Esaulkova, Renata A Kadyrova, Dar'ya V Spiridonova, Andrew S Drachuk, Vitali M Boitsov and 1 more
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In one paragraphArticle in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
11 authors.
Anastasia V EgorovaDepartment of Organic Chemistry, St. Petersburg State Institute of Technology, 190013 St. Petersburg, Russia.ORCID 0000-0002-0057-4202 Anastasia M LobovaDepartment of Organic Chemistry, St. Petersburg State Institute of Technology, 190013 St. Petersburg, Russia.
Dmitrii M EgorovDepartment of Organic Chemistry, St. Petersburg State Institute of Technology, 190013 St. Petersburg, Russia.
Elizaveta A TishchenkoDepartment of Chemical Technology of Organic Dyes and Phototropic Compounds, St. Petersburg State Institute of Technology, 190013 St. Petersburg, Russia.
Alexandrina S VolobuevaSaint-Petersburg Pasteur Institute, 197101 St. Petersburg, Russia.
Renata A KadyrovaSaint-Petersburg Pasteur Institute, 197101 St. Petersburg, Russia.
Dar'ya V SpiridonovaInstitute of Chemistry, St. Petersburg State University, 199034 St. Petersburg, Russia.ORCID 0000-0003-2823-0986 Andrew S DrachukLaboratory of Nanobiotechnologies, St. Petersburg National Research Academic University of the Russian Academy of Science (Alferov University), 194021 St. Petersburg, Russia.ORCID 0009-0009-2990-5958 Vitali M BoitsovLaboratory of Nanobiotechnologies, St. Petersburg National Research Academic University of the Russian Academy of Science (Alferov University), 194021 St. Petersburg, Russia.ORCID 0000-0002-4857-2046 Daria S NovikovaDepartment of Chemical Technology of Organic Dyes and Phototropic Compounds, St. Petersburg State Institute of Technology, 190013 St. Petersburg, Russia.ORCID 0000-0002-5310-4570 Funding
Russian Science Foundation 24-73-10221
6 · The paper itselfAbstract
This work focuses on rapid, catalyst-free synthesis of a new series of acetylenic phosphonates as promising building blocks for creating antiviral and anticancer agents. A comprehensive assessment of the biological activity of the synthesized compounds was conducted. Dialkyl phosphonates
Indexed as
AcetyleneAntineoplastic AgentsAntiviral AgentsOrganophosphonatesCell Line, TumorCell ProliferationHumansInfluenza A Virus, H1N1 SubtypeMolecular Docking SimulationMolecular StructureStructure-Activity RelationshipAcetyleneAntineoplastic AgentsAntiviral AgentsOrganophosphonatesacetylenesanticancer activityH1N1molecular dockingphosphonates
Identifiers
PMID42280164
PMCPMC13257472
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