Evidence map›Paper›PMID 42280041›Full record

ArticleMaterials (Basel, Switzerland)2026

Ammonium Glycyrrhizinate-Reinforced Dual-Network Poly(Thioctic Acid)-Based Hydrogel Dressing with Robust Wet Adhesion, Antibacterial Activity and Oxidative Stress Regulation.

Ziming Cheng, Zhiyuan Zhang, Huanfu Lu, Jiawei Zhang, Yang Yuan, Fangzheng Yu, Chen Wang, Jiale He, Zheng Zhao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ziming ChengState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan 430070, China.
Zhiyuan ZhangState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan 430070, China.
Huanfu LuHainan Finsen Medical Devices Co., Ltd., Haikou 570100, China.
Jiawei ZhangState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan 430070, China.
Yang YuanState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan 430070, China.
Fangzheng YuState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan 430070, China.
Chen WangState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan 430070, China.
Jiale HeState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan 430070, China.
Zheng ZhaoState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan 430070, China.

Funding

Hainan Provincial Sanya Yazhou Bay Science and Technology Innovation Joint Project ZDYF2025GXJS141Wuhan Metropolitan Area Collaborative Technology Innovation Project 2025070604020039
6 · The paper itself

Abstract

Developing hydrogel dressings that simultaneously achieve robust wet tissue adhesion, mechanical stability, antibacterial activity, and oxidative stress regulation remains challenging. In this study, a dual-network poly (thioctic acid)/ammonium glycyrrhizinate (PTA/AG) hydrogel was developed through thermally induced ring-opening polymerization (ROP) of TA and sodium thioctate (TA-Na) to form a primary network, followed by the formation of an AG-driven secondary network during cooling. TA-Na improved the aqueous processability of TA, while the AG secondary network reinforced the stability of the PTA primary network. The resulting hydrogel exhibited a crossover strain of 454% and a wet adhesion strength of up to 16.37 kPa on porcine skin. In addition, the hydrogel showed strong antibacterial activity against

Indexed as

antibacterial activityantioxidant activitydual-networkwet tissue adhesion

Identifiers

PMID42280041
PMCPMC13258303

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.