Suspected and Non-Targeted Screening of Non-Edible Substances in Food by UPLC-Q-TOF-MS.

Ting Wang, Fuhong Chen, Lirong Pan, Wenxuan Yuan, Jie Pang, Xianliang Li, Cunxian Xi, Dunming Xu

Abstract read

In one paragraph

Article in Foods (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ting WangTechnical Center of Xiamen Customs, Xiamen 361026, China.

Fuhong ChenTechnical Center of Xiamen Customs, Xiamen 361026, China.

Lirong PanTechnical Center of Xiamen Customs, Xiamen 361026, China.

Wenxuan YuanTechnical Center of Xiamen Customs, Xiamen 361026, China.

Jie PangCollege of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China.ORCID 0000-0002-7061-5233

Xianliang LiTechnical Center of Chongqing Customs, Chongqing 401147, China.

Cunxian XiTechnical Center of Chongqing Customs, Chongqing 401147, China.

Dunming XuTechnical Center of Xiamen Customs, Xiamen 361026, China.ORCID 0000-0002-9519-1393

Funding

Chongqing Technology Key Foundation CSTB2025TIAD-KPX0080Fujian Provincial Science&Technology Foundation the Fujian Provincial Science&Technology Foundation 2025Y0051National Key Research and Development Program of China 2023YFF1104900Xiamen Customs Research Project 2024XK12

6 · The paper itself

Abstract

A screening method based on dispersive solid-phase extraction (DSPE) coupled with ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry (UPLC-Q-TOF-MS) was established for the analysis of non-edible substances in food. This method is applicable to a wide range of non-edible substances, including but not limited to antihypertensive, hypoglycemic, weight-loss, antimicrobial, antipyretic-analgesic, sedative-hypnotic, and antifatigue agents. Through systematic optimization of sample pretreatment and UPLC-Q-TOF-MS conditions, ultrasonic extraction with methanol followed by cleanup using 25 mg Primary Secondary Amine (PSA) and 50 mg C

Indexed as

dispersive solid-phase extractionhigh-resolution mass spectrometrynon-edible substancesPDE-5 inhibitorssuspected screeningunknown structural analogues

Identifiers

PMID42279787

DOI10.3390/foods15112001

PMCPMC13257398

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.