Evidence map›Paper›PMID 42279605›Full record

ArticleDiagnostics (Basel, Switzerland)2026

Introduction of High-Sensitivity Troponin Assay to Rural Tertiary Care Medical Center: Impact on Subsequent Cardiac Diagnostic Testing.

Peter M Leonard, Alexandra Ortengren, Adam Z Spitz, Roshni Kalkur, Pablo Martinez-Camblor, Jose Mercado, Kerrilynn Hennessey, Cynthia C Taub

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Peter M LeonardDepartment of Internal Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH 03766, USA.ORCID 0009-0001-2692-6763
Alexandra OrtengrenDepartment of Cardiology, Heart and Vascular Center, Dartmouth Hitchcock Medical Center, Lebanon, NH 03766, USA.
Adam Z SpitzDepartment of Internal Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH 03766, USA.ORCID 0000-0001-9838-6260
Roshni KalkurDepartment of Internal Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH 03766, USA.
Pablo Martinez-CamblorDepartment of Anesthesiology, Dartmouth Hitchcock Medical Center, Lebanon, NH 03766, USA.ORCID 0000-0001-7845-3905
Jose MercadoDepartment of Internal Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH 03766, USA.ORCID 0009-0009-8988-831X
Kerrilynn HennesseyDepartment of Anesthesiology, Dartmouth Hitchcock Medical Center, Lebanon, NH 03766, USA.ORCID 0000-0001-9113-0369
Cynthia C TaubDepartment of Medicine, SUNY Upstate University Hospital, Syracuse, NY 13210, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-sensitivity cardiac troponin (hs-cTn) assay offers improved diagnostic accuracy for the detection of myocardial infarction but has seen slow adoption in the United States, particularly in rural settings. Limited research has explored the impact of hs-cTn implementation on downstream testing, in rural hospitals where diagnostic delays are common. This study evaluates the effects of transitioning from standard assay to hs-cTn in a rural tertiary care medical center. We conducted a retrospective analysis of de-identified data from four weeks before and after the implementation of an hs-cTn assay. We assessed the presence of downstream cardiovascular testing and consults among emergency department and inpatient chest pain encounters. Lengths of stay were evaluated. In total, 1664 pre- and 1479 post-implementation admissions were evaluated. Demographic characteristics and comorbidities were similar during the study period. Chest pain was reported more frequently during the post-hs-cTn implementation period as the chief complaint (21.4% vs. 28.7%;

Indexed as

cascade testingchest painhigh-sensitivity cardiac troponinrural hospitalsstress testing utilizationtroponin testing

Identifiers

PMID42279605
PMCPMC13256203

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.