Evidence map›Paper›PMID 42279462›Full record

ArticleDiagnostics (Basel, Switzerland)2026

Pre-Analytical and Analytical Challenges in Whole-Exome Sequencing of Formalin-Fixed Paraffin-Embedded Breast and Prostate Cancer Tissue: A Real-World Multicenter Study.

Mahira L Rosa, Cláudia Bordignon, Jaqueline B Schuch, Angélica C Baumont, Marina Bessel, Giovana D Curzel, Nathan A Cadore, Ana Paula M Varela, Giovana T Dos Santos, Tiago F Andreis and 22 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

Mahira L RosaHospital Moinhos de Vento, Porto Alegre 90540-000, RS, Brazil.ORCID 0000-0001-8569-9751
Cláudia BordignonHospital Moinhos de Vento, Porto Alegre 90540-000, RS, Brazil.
Jaqueline B SchuchHospital Moinhos de Vento, Porto Alegre 90540-000, RS, Brazil.ORCID 0000-0002-2195-4407
Angélica C BaumontHospital Moinhos de Vento, Porto Alegre 90540-000, RS, Brazil.
Marina BesselHospital Moinhos de Vento, Porto Alegre 90540-000, RS, Brazil.
Giovana D CurzelHospital Moinhos de Vento, Porto Alegre 90540-000, RS, Brazil.
Nathan A CadoreHospital Moinhos de Vento, Porto Alegre 90540-000, RS, Brazil.
Ana Paula M VarelaHospital Moinhos de Vento, Porto Alegre 90540-000, RS, Brazil.
Giovana T Dos SantosHospital Moinhos de Vento, Porto Alegre 90540-000, RS, Brazil.
Tiago F AndreisHospital Moinhos de Vento, Porto Alegre 90540-000, RS, Brazil.ORCID 0000-0001-7098-033X
Francine H OliveiraHospital Moinhos de Vento, Porto Alegre 90540-000, RS, Brazil.
Vitor F VasconcellosHospital Universitário Cassiano Antônio Moraes, Vitória 29040-090, ES, Brazil.
Lilian A R BarrosInstituto Brasileiro de Controle do Câncer, São Paulo 03164-000, SP, Brazil.
Cristiano P SouzaHospital de Câncer de Barretos, Barretos 14784-400, SP, Brazil.ORCID 0000-0002-6412-8041
Williams F BarraNúcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém 66073-005, PA, Brazil.
Daniela L C LouzeiroHospital de Oncologia Dr. Tarquinio Lopes Filho, São Luís 65076-090, MA, Brazil.
Alessandra NotariHospital Escola da Universidade Federal de Pelotas, Empresa Brasileira de Serviços Hospitalares (EBSERH), Pelotas 96020-360, RS, Brazil.
Juliana J de MenezesHospital Nossa Senhora da Conceição, Porto Alegre 91350-200, RS, Brazil.
Pedro E R LiedkeHospital de Clínicas de Porto Alegre, Porto Alegre 90035-903, RS, Brazil.ORCID 0000-0002-8298-4765
Gláucio A BertolloAssociação Feminina de Educação e Combate ao Câncer (AFECC), Hospital Santa Rita de Cássia, Vitória 29052-010, ES, Brazil.ORCID 0009-0001-4173-8613
Aline B L GongoraHospital do Câncer UOPECCAN, Cascavel 85807-200, PR, Brazil.
Henrique G AscencoHospital Universitário Maria Aparecida Pedrossian, Campo Grande 79080-190, MS, Brazil.
Eduardo Kowalski-NetoHospital Calixto Midlej Filho, Santa Casa de Misericórdia de Itabuna, Itabuna 45603-050, BA, Brazil.
Christina P OppermannHospital Fêmina, Porto Alegre 90540-000, RS, Brazil.
Gustavo WerutskyHospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre 90610-000, RS, Brazil.
Edilmar M SantosLiga Norte Riograndense Contra o Câncer, Natal 59075-740, RN, Brazil.
Flavio S BrandãoSanta Casa de Belo Horizonte, Belo Horizonte 30150-221, MG, Brazil.ORCID 0009-0001-7590-3269
Ruffo FreitasHospital Araújo Jorge, Associação de Combate ao Câncer em Goiás, Goiânia 74605-050, GO, Brazil.ORCID 0000-0003-4145-8598
Angélica Nogueira-RodriguesFaculty of Medicine, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, MG, Brazil.ORCID 0000-0002-3405-8310
André L C ManciniHospital Universitário Getúlio Vargas, Manaus 69020-170, AM, Brazil.
Daniela D RosaHospital Moinhos de Vento, Porto Alegre 90540-000, RS, Brazil.
Gabriel S MacedoHospital Moinhos de Vento, Porto Alegre 90540-000, RS, Brazil.

Funding

Hospital Moinhos de Vento NA
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

breast neoplasmsexome sequencingprecision medicineprostatic neoplasms

Identifiers

PMID42279462
PMCPMC13256900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.