ArticleCancers2026
Proteome Responses to Acute Inhibition of De Novo Sphingolipid Synthesis Suggest Cancer Combination Therapies.
Thi Thu Trang Luu, Dakai Zhang, Khaggeswar Bheemanapally, Masihuz Zaman, Zhiping Wu, Yang Liu, Xiaoqin Wu, Hyun-Eui Kim, Lei Zheng, Besim Ogretmen and 2 more
Abstract read
In one paragraphArticle in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
12 authors.
Thi Thu Trang LuuMolecular & Translational Biology Program, MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030, USA.
Dakai ZhangDepartment of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.ORCID 0000-0002-6232-7776 Khaggeswar BheemanapallyDepartments of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Masihuz ZamanDepartments of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Zhiping WuDepartments of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Yang LiuMolecular & Translational Biology Program, MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030, USA.
Xiaoqin WuMolecular & Translational Biology Program, MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030, USA.
Hyun-Eui KimMolecular & Translational Biology Program, MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030, USA.ORCID 0000-0003-1495-1993 Lei ZhengMolecular & Translational Biology Program, MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030, USA.ORCID 0000-0001-7789-5234 Besim OgretmenDepartment of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC 29425, USA.ORCID 0000-0002-1019-5660 Junmin PengDepartments of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.ORCID 0000-0003-0472-7648 Guangwei DuMolecular & Translational Biology Program, MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030, USA.ORCID 0000-0003-4193-6975 Funding
Training Interdisciplinary Pharmacology Scientists (TIPS)T32GM139801 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Carmen W. Dessauer · 2021 to 2026
$1.5MNIH HHS 1C06RR018823-01NIH HHS 1R01AG092468-01NIH HHS 5P30CA138313-17NIH HHS 5P30DK056338-22NIH HHS 5R00AA029146-05NIH HHS 5RR017677-05NIH HHS T32GM139801
6 · The paper itselfAbstract
PubMed holds no abstract for this paper.
Indexed as
cancercholesterol synthesiscombination therapyde novo sphingolipid synthesislysosomemyriocinproteome
Identifiers
PMID42279409
PMCPMC13256006
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