Evidence map›Paper›PMID 42279263›Full record

ReviewCancers2026

Biomarker-Stratified Efficacy of Immune Checkpoint Inhibitors in Locally Advanced Head and Neck Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis of Randomized Trials.

Ramaditya Srinivasmurthy, Daniel T Jones, Rishi K Nanda, Jason Ta, Abbas Hussain, Riccesha Hattin, Sisi Tian, Suparna Shah, Jo-Lawrence Bigcas, Robert Wang and 2 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ramaditya SrinivasmurthyDepartment of Internal Medicine, Mount Sinai Morningside/West, New York, NY 10019, USA.
Daniel T JonesDepartment of Internal Medicine, Sunrise Health GME Consortium, Las Vegas, NV 89128, USA.
Rishi K NandaCollege of Osteopathic Medicine, Touro University Nevada, Las Vegas, NV 89014, USA.
Jason TaDepartment of Internal Medicine, HCA Healthcare/USF Morsani College of Medicine GME: HCA Florida Citrus Hospital, Inverness, FL 34452, USA.ORCID 0009-0005-8514-2781
Abbas HussainDepartment of Internal Medicine, Kirk Kerkorian School of Medicine at UNLV, Las Vegas, NV 89102, USA.
Riccesha HattinDepartment of Internal Medicine, Kirk Kerkorian School of Medicine at UNLV, Las Vegas, NV 89102, USA.
Sisi TianDepartment of Otolaryngology, Kirk Kerkorian School of Medicine at UNLV, Las Vegas, NV 89102, USA.
Suparna ShahDepartment of Otolaryngology, Kirk Kerkorian School of Medicine at UNLV, Las Vegas, NV 89102, USA.
Jo-Lawrence BigcasDepartment of Otolaryngology Head and Neck Surgery, University of California San Diego School of Medicine, La Jolla, CA 92093, USA.
Robert WangDepartment of Otolaryngology, Kirk Kerkorian School of Medicine at UNLV, Las Vegas, NV 89102, USA.
Samual FrancisDivision of Radiation Oncology, Comprehensive Cancer Centers of Nevada, Las Vegas, NV 89169, USA.
Kyaw Z TheinDivision of Hematology and Medical Oncology, Comprehensive Cancer Centers of Nevada, Las Vegas, NV 89169, USA.ORCID 0000-0003-1518-1097

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

head and neck carcinomaICIimmune checkpoint inhibitorsimmunotherapyLAHNSCClocally advancedPD-L1

Identifiers

PMID42279263
PMCPMC13255863

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.