Evidence map›Paper›PMID 42278938›Full record

ReviewJournal of clinical medicine2026

AI in Musculoskeletal Imaging: An End-to-End Perspective.

Domenico Albano, Mariachiara Basile, Stefano Fusco, Luigi Asmundo, Salvatore Gitto, Carmelo Messina, Alessio Piacentini, Francesco Rizzetto, Caterina Beatrice Monti, Moreno Zanardo and 2 more

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Domenico AlbanoDepartment of Radiology, ASST Grande Ospedale Metropolitano Niguarda, Piazza Ospedale Maggiore 3, 20162 Milan, Italy.ORCID 0000-0001-7989-9861
Mariachiara BasileDipartimento di Scienze Biomediche per la Salute, Università Degli Studi di Milano, Via Mangiagalli 31, 20133 Milan, Italy.
Stefano FuscoDipartimento di Scienze Biomediche per la Salute, Università Degli Studi di Milano, Via Mangiagalli 31, 20133 Milan, Italy.
Luigi AsmundoDepartment of Radiology, ASST Grande Ospedale Metropolitano Niguarda, Piazza Ospedale Maggiore 3, 20162 Milan, Italy.ORCID 0000-0002-1410-341X
Salvatore GittoDipartimento di Scienze Biomediche per la Salute, Università Degli Studi di Milano, Via Mangiagalli 31, 20133 Milan, Italy.ORCID 0000-0002-3623-7822
Carmelo MessinaDipartimento di Scienze Biomediche per la Salute, Università Degli Studi di Milano, Via Mangiagalli 31, 20133 Milan, Italy.
Alessio PiacentiniDipartimento di Scienze Biomediche per la Salute, Università Degli Studi di Milano, Via Mangiagalli 31, 20133 Milan, Italy.ORCID 0000-0001-5266-7251
Francesco RizzettoDepartment of Radiology, ASST Grande Ospedale Metropolitano Niguarda, Piazza Ospedale Maggiore 3, 20162 Milan, Italy.ORCID 0000-0003-3451-9874
Caterina Beatrice MontiDepartment of Radiology, ASST Grande Ospedale Metropolitano Niguarda, Piazza Ospedale Maggiore 3, 20162 Milan, Italy.
Moreno ZanardoIRCCS Ospedale Galeazzi-Sant'Ambrogio, Via Cristina Belgioioso 173, 20157 Milan, Italy.ORCID 0000-0001-9640-8534
Angelo VanzulliDepartment of Radiology, ASST Grande Ospedale Metropolitano Niguarda, Piazza Ospedale Maggiore 3, 20162 Milan, Italy.ORCID 0000-0002-2452-3370
Luca Maria SconfienzaDipartimento di Scienze Biomediche per la Salute, Università Degli Studi di Milano, Via Mangiagalli 31, 20133 Milan, Italy.ORCID 0000-0003-0759-8431

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Artificial intelligence (AI) is increasingly reshaping musculoskeletal (MSK) imaging across the entire imaging pathway. This narrative review summarizes current AI applications in MSK radiology across four domains: acquisition and reconstruction, detection and triage, characterization and quantification, and prognosis and decision support. AI-based reconstruction has enabled faster MRI acquisitions, improved denoising and artifact reduction, and supported low-dose CT imaging while preserving diagnostic quality. Fracture detection and triage currently represent the most mature clinical applications, particularly in emergency settings. AI is also promoting a shift from qualitative interpretation to quantitative imaging phenotyping through automated assessment of body composition, cartilage, bone density, degenerative spine disease, skeletal maturity, and lesion heterogeneity. Emerging applications in prognostic modeling, implant evaluation, and multimodal risk stratification remain promising but less mature. Broader clinical implementation is still limited by restricted interpretability, dataset bias, insufficient prospective validation, regulatory complexity, and unresolved medico-legal issues. Overall, AI should be viewed as a tool to augment, not replace, radiological expertise.

Indexed as

artificial intelligencemusculoskeletal imaging

Identifiers

PMID42278938
PMCPMC13257737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.