Evidence map›Paper›PMID 42278659›Full record

ArticleInternational journal of molecular sciences2026

Exploring the Role of Macrophage Marker CD68 in Pediatric Acute Myeloid Leukemia.

Laurens Van Camp, Jolien Vanhooren, Barbara Depreter, Mattias Hofmans, Inge D'Hont, Christophe Chantrain, Laurence Dedeken, An Van Damme, Anne Uyttebroeck, Tim Lammens and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Laurens Van CampDepartment of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, 9000 Ghent, Belgium.ORCID 0000-0002-5485-7021
Jolien VanhoorenDepartment of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, 9000 Ghent, Belgium.ORCID 0000-0002-2604-0727
Barbara DepreterDepartment of Laboratory Medicine, AZ Delta General Hospital, 8800 Roeselare, Belgium.ORCID 0000-0002-5019-1672
Mattias HofmansCancer Research Institute Ghent (CRIG), 9000 Ghent, Belgium.ORCID 0000-0003-2061-7617
Inge D'HontDepartment of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, 9000 Ghent, Belgium.ORCID 0000-0002-5487-6994
Christophe ChantrainDivision of Pediatric Hematology-Oncology, Centre Hospitalier Chrétien (CHC), MontLégia, 4000 Liege, Belgium.ORCID 0000-0003-0272-9367
Laurence DedekenDepartment of Pediatric Hematology-Oncology, Hôpital Universitaire des Enfants Reine Fabiola, 1020 Brussels, Belgium.ORCID 0000-0001-7829-6428
An Van DammeDepartment of Pediatric Hematology Oncology, Cliniques Universitaires Saint-Luc, 1200 Brussels, Belgium.ORCID 0000-0002-7114-201X
Anne UyttebroeckDepartment of Pediatrics, University Hospital Gasthuisberg, 3000 Leuven, Belgium.ORCID 0000-0001-5644-424X
Tim LammensDepartment of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, 9000 Ghent, Belgium.ORCID 0000-0001-8733-4027
Barbara De MoerlooseDepartment of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, 9000 Ghent, Belgium.ORCID 0000-0002-2449-539X

Funding

Kinderkankerfonds vzwKom Op Tegen KankerOlivia Hendrickx Research Fund vzw
6 · The paper itself

Abstract

Pediatric acute myeloid leukemia (pedAML) is a childhood malignancy with relapse rates of approximately 30%. CD68, a macrophage marker involved in phagocytosis and macrophage recruitment, may contribute to AML biology. We analyzed

Indexed as

Antigens, CDAntigens, Differentiation, MyelomonocyticBiomarkers, TumorLeukemia, Myeloid, AcuteMacrophagesCD68 MoleculeCell Line, TumorCell ProliferationChildChild, PreschoolEpithelial-Mesenchymal TransitionFemaleHumansMaleAntigens, CDAntigens, Differentiation, MyelomonocyticBiomarkers, TumorCD68 antigen, humanCD68 MoleculeAMLbiologyCD68macrophage markerpediatric acute myeloid leukemiatargeted therapy

Identifiers

PMID42278659
PMCPMC13257172

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.