Control of Schwann Cell Myelination by DDR1 Receptor Tyrosine Kinase.

Mengyuan Fan, Yuchen Sun, Ruyi Mei, Wenwen Lu, Xiaofeng Zhao, Aifen Yang, Mengsheng Qiu

Abstract read

In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mengyuan FanCollege of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.

Yuchen SunCollege of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.

Ruyi MeiPerioperative and Systems Medicine Laboratory, Zhejiang University School of Medicine, National Clinical Research Center for Children and Adolescents' Health and Diseases, Hangzhou 310052, China.

Wenwen LuCollege of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.

Xiaofeng ZhaoCollege of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.

Aifen YangCollege of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.

Mengsheng QiuCollege of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.

Funding

National Natural Science Foundation of China 32371022

6 · The paper itself

Abstract

In peripheral nervous system (PNS), immature Schwann cells differentiate into two functionally distinct types of mature Schwann cells: myelinating Schwann cells, which establish a one-to-one relationship with large-diameter axons and initiate the complex myelination program that enables the rapid saltatory conduction of nerve impulses, and non-myelinating Schwann cells, which envelop multiple small-diameter axons without forming myelin, but support axon survival and maintain microenvironment homeostasis. Here, we demonstrate that discoidin domain receptor 1 (DDR1) signaling plays a pivotal role in Schwann cell maturation and peripheral nerve myelination.

Indexed as

Discoidin Domain Receptor 1Myelin SheathSchwann CellsAnimalsAxonsCell DifferentiationFemaleMaleMAP Kinase Signaling SystemMiceMice, KnockoutSignal TransductionDdr1 protein, mouseDiscoidin Domain Receptor 1DDR1differentiationERKmyelinationSchwann cells

Identifiers

PMID42278657

DOI10.3390/ijms27115135

PMCPMC13258737

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.