Evidence map›Paper›PMID 42278602›Full record

ArticleInternational journal of molecular sciences2026

Nrf2 Levels in Human Semen and Spermatozoa: Association with F

Elena Moretti, Cinzia Signorini, Laura Liguori, Elena Leoni, Giulia Collodel

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elena MorettiDepartment of Molecular and Developmental Medicine, University of Siena, 53100 Siena, Italy.ORCID 0000-0002-9467-0501
Cinzia SignoriniDepartment of Molecular and Developmental Medicine, University of Siena, 53100 Siena, Italy.ORCID 0000-0003-0006-9414
Laura LiguoriDepartment of Molecular and Developmental Medicine, University of Siena, 53100 Siena, Italy.ORCID 0009-0008-5563-236X
Elena LeoniDepartment of Molecular and Developmental Medicine, University of Siena, 53100 Siena, Italy.ORCID 0009-0000-2360-0613
Giulia CollodelDepartment of Molecular and Developmental Medicine, University of Siena, 53100 Siena, Italy.ORCID 0000-0003-1587-0159

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the recognized role of oxidative stress (OS) in sperm function, limited data exist on Nuclear factor-E2-related factor 2 (Nrf2) pathway modulation in relation to reliable oxidative damage markers in human semen. In this study, 79 semen samples were collected from men undergoing semen analysis and grouped as varicocele (V, no. 22), urogenital infections (UI, no. 23), unknown fertility status without pathologies (UFS, no. 15), and fertile controls (F, no. 19). After semen analysis, ELISA were used to quantify F

Indexed as

F2-IsoprostanesLipid PeroxidationNF-E2-Related Factor 2SemenSpermatozoaAdultBiomarkersHumansMaleOxidative StressSemen AnalysisSperm MotilityBiomarkersF2-IsoprostanesNFE2L2 protein, humanNF-E2-Related Factor 2F2-Isoprostaneshuman semenNrf2 pathwayurogenital infectionsvaricocele

Identifiers

PMID42278602
PMCPMC13256952

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.