Evidence map›Paper›PMID 42278515›Full record

ArticleInternational journal of molecular sciences2026

Molecular and Functional Interactions Between Cisplatin and Nicotinamide: A Combined Computational, Spectroscopic, and Biological Study.

Beata Szefler, Magdalena Wujak, Agnieszka Skotnicka, Krzysztof Skowron, Julia Czuba, Przemysław Czeleń, Kamil Szupryczyński, Piotr Cysewski

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Beata SzeflerDepartment of Physical Chemistry, Faculty of Pharmacy, Collegium Medicum, Nicolaus Copernicus University, Kurpińskiego 5, 85-096 Bydgoszcz, Poland.ORCID 0000-0001-8433-3520
Magdalena WujakDepartment of Medicinal Chemistry, Faculty of Pharmacy, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, Jurasza 2, 85-089 Bydgoszcz, Poland.ORCID 0000-0002-4243-8161
Agnieszka SkotnickaFaculty of Chemical Technology and Engineering, Bydgoszcz University of Science and Technology, Seminaryjna 3, 85-326 Bydgoszcz, Poland.ORCID 0000-0002-7286-2692
Krzysztof SkowronDepartment of Microbiology, Faculty of Pharmacy, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, M. Curie Skłodowskiej 9, 85-094 Bydgoszcz, Poland.ORCID 0000-0003-0868-864X
Julia CzubaDepartment of Microbiology, Faculty of Pharmacy, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, M. Curie Skłodowskiej 9, 85-094 Bydgoszcz, Poland.ORCID 0009-0000-9289-4483
Przemysław CzeleńDepartment of Physical Chemistry, Faculty of Pharmacy, Collegium Medicum, Nicolaus Copernicus University, Kurpińskiego 5, 85-096 Bydgoszcz, Poland.ORCID 0000-0001-7268-4956
Kamil SzupryczyńskiFaculty of Pharmacy, Doctoral School of Medical and Health Sciences, Collegium Medicum, Nicolaus Copernicus University, Jagiellońska 13, 85-067 Bydgoszcz, Poland.
Piotr CysewskiDepartment of Physical Chemistry, Faculty of Pharmacy, Collegium Medicum, Nicolaus Copernicus University, Kurpińskiego 5, 85-096 Bydgoszcz, Poland.ORCID 0000-0001-6220-2634

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cisplatin remains a widely used anticancer agent; however, its effectiveness can be influenced by systemic toxicity, resistance mechanisms, and interactions with exogenous compounds. Nicotinamide (vitamin B3), an NAD

Indexed as

Antineoplastic AgentsCisplatinNiacinamideA549 CellsCell Line, TumorHumansModels, MolecularThermodynamicsAntineoplastic AgentsCisplatinNiacinamideanticancer activityantimicrobial activitycisplatinlung cancermolecular modellingnicotinamide

Identifiers

PMID42278515
PMCPMC13257153

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.