Evidence map›Paper›PMID 42278511›Full record

ArticleInternational journal of molecular sciences2026

Heterozygous Nonsense Mutation in the Nuclear Transport Factor

Tammy Benteau, Nelly Abdelfatah, Anne Griffin, Cindy Penney, Pingzhao Hu, Susan G Stanton, Guangju Zhai, Maxime Maheu, Curtis R French, Terry-Lynn Young

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tammy BenteauDivision of Biomedical Science, Faculty of Medicine, Memorial University, St. John's, NL A1B 3V6, Canada.
Nelly AbdelfatahDivision of Biomedical Science, Faculty of Medicine, Memorial University, St. John's, NL A1B 3V6, Canada.
Anne GriffinDivision of Biomedical Science, Faculty of Medicine, Memorial University, St. John's, NL A1B 3V6, Canada.
Cindy PenneyDivision of Biomedical Science, Faculty of Medicine, Memorial University, St. John's, NL A1B 3V6, Canada.
Pingzhao HuDepartment of Biochemistry and Computer Science, Western University, London, ON N6G 2V4, Canada.
Susan G StantonNational Centre for Audiology & School of Communication Sciences and Disorders, Faculty of Health Sciences, Western University, London, ON N6G 1H1, Canada.
Guangju ZhaiDivision of Biomedical Science, Faculty of Medicine, Memorial University, St. John's, NL A1B 3V6, Canada.
Maxime MaheuÉcole d'Orthophonie et d'Audiologie, Université de Montréal, Montréal, QC H3C 3J7, Canada.ORCID 0000-0003-4032-0730
Curtis R FrenchDivision of Biomedical Science, Faculty of Medicine, Memorial University, St. John's, NL A1B 3V6, Canada.
Terry-Lynn YoungDivision of Biomedical Science, Faculty of Medicine, Memorial University, St. John's, NL A1B 3V6, Canada.ORCID 0000-0003-4673-6470

Funding

Canadian Foundation of Innovation 9384, 13120CIHR 222294Excite Corporation PartnershipGenome Canada AMGGIGovernment of Newfoundland and Labrador Innovation FundMemorial University of Newfoundland Student Stipends
6 · The paper itself

Abstract

Otosclerosis is a common cause of conductive hearing loss thought to result from dysregulated bone remodeling in the embryonic tissues of the globuli interossei. Both familial and sporadic cases have been reported. To date, 10 published

Indexed as

alpha KaryopherinsCodon, NonsenseOtosclerosisFemaleGenes, DominantHeterozygoteHumansPedigreealpha KaryopherinsCodon, Nonsenseautosomal dominantconductive hearing lossglobuli interosseiImportin-αImportin-βKPNA7ncNLS transportotosclerosisOTSCRELN

Identifiers

PMID42278511
PMCPMC13256754

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.