Evidence map›Paper›PMID 42278506›Full record

ArticleInternational journal of molecular sciences2026

Pre-Activation of Mitophagy Protects Against Hyperbaric Oxygen-Induced Central Nervous System Oxygen Toxicity.

Wei Ding, Qi Zhu, Houyu Zhao, Guanning Wei, Guoyang Huang, Jing Shi, Longfei Wang, Nan Zhao, Jin Ding, Yiqun Fang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wei DingNaval Medical Center, Naval Medical University, Shanghai 200433, China.
Qi ZhuNaval Medical Center, Naval Medical University, Shanghai 200433, China.ORCID 0000-0003-1855-5568
Houyu ZhaoNaval Medical Center, Naval Medical University, Shanghai 200433, China.
Guanning WeiTranslational Medical Research Center, Naval Medical University, Shanghai 200433, China.ORCID 0000-0002-5086-1787
Guoyang HuangNaval Medical Center, Naval Medical University, Shanghai 200433, China.
Jing ShiNaval Medical Center, Naval Medical University, Shanghai 200433, China.
Longfei WangNaval Medical Center, Naval Medical University, Shanghai 200433, China.
Nan ZhaoNaval Medical Center, Naval Medical University, Shanghai 200433, China.
Jin DingTranslational Medical Research Center, Naval Medical University, Shanghai 200433, China.
Yiqun FangNaval Medical Center, Naval Medical University, Shanghai 200433, China.

Funding

Discipline Development Program in Diving Medicine 25XKQ0003Pre-research Project 21JMRH002Technology application advancement project 21AH0103
6 · The paper itself

Abstract

Central nervous system oxygen toxicity (CNS-OT) is a major complication of hyperbaric oxygen (HBO) characterized by seizures and neuronal damage, yet the underlying mechanisms remain incompletely understood. Using male Sprague Dawley rats (n = 6 per group) and HT22 neurons exposed to either HBO (6 ATA, 100% O

Indexed as

Central Nervous SystemHyperbaric OxygenationMitophagyOxygenAnimalsApoptosisHeLa CellsHumansMaleMAP Kinase Signaling SystemMembrane Potential, MitochondrialMitochondriaNeuronsRatsRats, Sprague-DawleyUbiquitin-Protein LigasesOxygenparkin proteinUbiquitin-Protein Ligasescentral nervous system oxygen toxicity (CNS-OT)hyperbaric oxygenmitophagyneuroprotection

Identifiers

PMID42278506
PMCPMC13256620

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.