Evidence map›Paper›PMID 42278405›Full record

ArticleInternational journal of molecular sciences2026

Feedback Loop of DUXAP8/miR-214-3p/KLF13 Facilitates Hepatocellular Carcinoma Progression and Serves as an Indicator of Tumor Microenvironment via Impacting Piezo1.

Yifan Zhang, Xinyi Luo, Yiquan Lu, Fengjie Hao, Xiaochun Fei, Yongjun Chen, Junqing Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yifan ZhangDepartment of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197, Rui Jin Er Road, Shanghai 200025, China.
Xinyi LuoDepartment of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197, Rui Jin Er Road, Shanghai 200025, China.
Yiquan LuDepartment of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197, Rui Jin Er Road, Shanghai 200025, China.
Fengjie HaoDepartment of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197, Rui Jin Er Road, Shanghai 200025, China.
Xiaochun FeiDepartment of Pathology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197, Rui Jin Er Road, Shanghai 200025, China.
Yongjun ChenDepartment of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197, Rui Jin Er Road, Shanghai 200025, China.
Junqing WangDepartment of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197, Rui Jin Er Road, Shanghai 200025, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pseudogenes are barely transcribed normally, but some of them are transcribed as long non-coding RNAs during tumorigenesis. The pathological features of pseudogenes in hepatocellular carcinoma (HCC) have not been illustrated clearly. Here, we engaged the pseudogene

Indexed as

Carcinoma, HepatocellularFeedback, PhysiologicalIon ChannelsLiver NeoplasmsTumor MicroenvironmentAnimalsApoptosisCell Cycle ProteinsCell Line, TumorCell ProliferationDisease ProgressionHumansKruppel-Like Transcription FactorsMaleMiceMice, Inbred BALB CCell Cycle ProteinsIon ChannelsKLF13 protein, humanKruppel-Like Transcription Factorslong non-coding RNA DUXAP8, humanMicroRNAsMIRN214 microRNA, humanPIEZO1 protein, humanRepressor ProteinsRNA, Long Noncodingfeedback loopHCCPiezo1pseudogene DUXAP8tumorigenesis

Identifiers

PMID42278405
PMCPMC13256093

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.