Evidence map›Paper›PMID 42278345›Full record

ArticleInternational journal of molecular sciences2026

An Aqueous Extract of

Elisa Bisconti, Fabrizio Barozzi, Erika Stefàno, Ilaria Serra, Francesco Vari, Giulia Vergine, Marina Damato, Rocco Placì, Francesco Paolo Fanizzi, Dario Domenico Lofrumento and 5 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Elisa BiscontiDepartment of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento, 73100 Lecce, Italy.ORCID 0009-0005-4339-3849
Fabrizio BarozziDepartment of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento, 73100 Lecce, Italy.ORCID 0000-0003-1409-2324
Erika StefànoDepartment of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento, 73100 Lecce, Italy.
Ilaria SerraDepartment of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento, 73100 Lecce, Italy.ORCID 0009-0005-4796-8881
Francesco VariDepartment of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento, 73100 Lecce, Italy.ORCID 0009-0005-5521-9864
Giulia VergineDepartment of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento, 73100 Lecce, Italy.
Marina DamatoDepartment of Experimental Medicine (DiMeS), University of Salento, 73100 Lecce, Italy.ORCID 0000-0003-0104-4323
Rocco PlacìDepartment of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento, 73100 Lecce, Italy.ORCID 0009-0008-6131-2880
Francesco Paolo FanizziDepartment of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento, 73100 Lecce, Italy.ORCID 0000-0003-3073-5772
Dario Domenico LofrumentoDepartment of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento, 73100 Lecce, Italy.ORCID 0000-0002-0106-3615
Gian Pietro Di SansebastianoDepartment of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento, 73100 Lecce, Italy.ORCID 0000-0001-5388-0695
Francesca BaldassarreDepartment of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento, 73100 Lecce, Italy.ORCID 0000-0002-3328-7701
Daniele VergaraDepartment of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento, 73100 Lecce, Italy.ORCID 0000-0002-2396-7674
Anna Maria GiudettiDepartment of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento, 73100 Lecce, Italy.ORCID 0000-0002-9204-040X
Giuseppe CiccarellaDepartment of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento, 73100 Lecce, Italy.ORCID 0000-0003-4467-0922

Funding

Ministry of Economic Development B89J23001360005
6 · The paper itself

Abstract

Epidermal lipid homeostasis is crucial for skin barrier integrity. This study investigated the effects of an aqueous extract from

Indexed as

Beta vulgarisKeratinocytesLipid MetabolismPlant ExtractsCell LineDiacylglycerol O-AcyltransferaseHaCaT CellsHumansNF-E2-Related Factor 2Oxidative StressPerilipin-2Reactive Oxygen SpeciesTriglyceridesDiacylglycerol O-AcyltransferaseNF-E2-Related Factor 2Perilipin-2Plant ExtractsPLIN2 protein, humanReactive Oxygen SpeciesTriglyceridesBeta vulgariskeratinocyteslipid dropletslipotoxicityoxidative stress

Identifiers

PMID42278345
PMCPMC13256935

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.