Evidence map›Paper›PMID 42278087›Full record

ReviewAnimals : an open access journal from MDPI2026

The Role of Natural Anthelmintics in Small Ruminant Health: A Global Narrative Review.

Tiziana Maria Mahayri, Alessia Serra, Filomena Dessì, Maria Piera Demontis, Maria Vittoria Varoni, Giuseppe Moniello, Giovanni Garippa

Abstract readReview
In one paragraph

Review in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tiziana Maria MahayriDepartment of Veterinary Medicine, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0001-5975-2272
Alessia SerraDepartment of Veterinary Medicine, University of Sassari, 07100 Sassari, Italy.ORCID 0009-0008-2076-1495
Filomena DessìDepartment of Veterinary Medicine, University of Sassari, 07100 Sassari, Italy.ORCID 0009-0001-5567-9263
Maria Piera DemontisDepartment of Veterinary Medicine, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0001-7414-9818
Maria Vittoria VaroniDepartment of Veterinary Medicine, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0003-3508-2053
Giuseppe MonielloDepartment of Veterinary Medicine, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-2593-7102
Giovanni GarippaDepartment of Veterinary Medicine, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-7235-5105

Funding

Fondazione di Sardegna FDS2223MONIELLO-CUP J83C22000160007University of Sassari Fondo di Ateneo per la Ricerca 2019University of Sassari Fondo di Ateneo per la Ricerca 2020
6 · The paper itself

Abstract

Gastrointestinal nematodes (GINs) represent a major and persistent threat to the health and productivity of small ruminants. Increasing anthelmintic resistance has made traditional drugs less effective, requiring sustainable alternatives. Among the most promising solutions are natural anthelmintics: bioactive compounds and organisms derived from plants, essential oils, condensed tannins, saponins, probiotics, and nematophagous fungi. These natural agents are not just supplementary but vital for integrated parasite control. This review examines the host-parasite relationship, focusing on resistance, tolerance, and resilience, and discusses the impact of GINs on productivity. It evaluates natural anthelmintics, including their mechanisms, efficacy, benefits, and safety. To ensure the successful integration of natural anthelmintics into mainstream parasite control programs, future research must prioritize real-world validation, longitudinal safety assessments, and comprehensive cost-benefit analyses.

Indexed as

gastrointestinal nematodesnatural anthelminticsproductive efficiencysmall ruminants

Identifiers

PMID42278087
PMCPMC13255622

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.